2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. Methylergometrine

Methylergometrine  (Synonyms: Methylergonovine; Ryegonovin free base; Spametrin F free base)

目录号: HY-153027
产品使用指南

摩尔计算器

Methylergometrine (Methylergonovine) 是一种具有口服活性的 5-HT2B 配体激动剂。Methylergometrine 的分布半衰期仅为 1-2 分钟。Methylergometrine 可作为催产药物，用于治疗子宫松弛。

该产品由公安部研究所生产，销售、运输全流程受严格监管。MCE 的所有产品仅用作科学研究或药证申报，请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

Methylergometrine Chemical Structure

Methylergometrine Chemical Structure

CAS No. : 113-42-8

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Methylergometrine 相关抗体

Top Publications Citing Use of Products

查看 5-HT Receptor 亚型特异性产品:

查看所有亚型
5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Methylergometrine (Methylergonovine) is an orally active 5-HT2B ligand agonist. The distribution half-life of Methylergometrine is only 1-2 min. Methylergometrine can be used as an oxytocin to treat uterine atony[1][2][3].

IC50 & Target[1]

5-HT2B Receptor

 

体内研究
(In Vivo)

Methylergometrine (0.2 mg/kg；静脉注射；单剂量) 出现在家兔子宫、肝脏和肾脏中，平均浓度分别为 34 ng/g、80 ng/g 和 203 ng/g (给药 30 min 后)[3]。
Methylergometrine 在家兔中的药代动力学 (PK) 参数[3]

CO ng/mL K12/min K21/min Ke1/min
mean 755.3 0.577 0.180 0.140
S.D. 215.8 0.098 0.036 0.069
T1/2α/min T1/2β/min Vdc L/kg Vdss L/kg Vdβ L/kg AUCtot (ng/mL)•min CLtot mL/min
mean 0.91 26.34 0.29 1.13 1.44 6060.88 83.74
S.D. 0.35 9.48 0.09 0.30 0.55 2005.30 17.86

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

339.43

Formula

C20H25N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Methylergometrine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methylergometrine113-42-8MethylergonovineRyegonovinSpametrin F5-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorRabbitsUterusLiverKidneysInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Methylergometrine
目录号：
HY-153027
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z