2. Others Neuronal Signaling Protein Tyrosine Kinase/RTK PI3K/Akt/mTOR Membrane Transporter/Ion Channel
  3. Isotope-Labeled Compounds Serotonin Transporter Trk Receptor PI3K Akt mTOR P-glycoprotein
  4. Levomilnacipran-d5 hydrochloride

Levomilnacipran-d5 hydrochloride  (Synonyms: 左旋米那普林-d5 (盐酸盐); (1S,2R)-Milnacipran-d5 hydrochloride; F-2695-d5 hydrochloride)

目录号: HY-B0168BS
产品使用指南 技术支持

Levomilnacipran-d5 ((1S,2R)-Milnacipran-d5) hydrochloride 是 Levomilnacipran hydrochloride (HY-B0168B) 氘代物。Levomilnacipran ((1S,2R)-Milnacipran) hydrochloride 是 Milnacipran (HY-B0168) 的对映异构体，也是能透过血脑屏障的 P-gp 强底物。Levomilnacipran hydrochloride 是 5-羟色胺和去甲肾上腺素再摄取抑制剂，对人去甲肾上腺素转运体 (NET) 和 5-羟色胺转运体 (SERT) 的 IC50 分别为 10.5 nM 和 19.0 nM，Ki 分别为 92.2 nM 和 1.2 nM。Levomilnacipran hydrochloride 具有抗抑郁与抗焦虑活性。Levomilnacipran hydrochloride 可用于抑郁症的研究。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Levomilnacipran-d<sub>5</sub> hydrochloride

Levomilnacipran-d5 hydrochloride Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
1 mg 询价
5 mg 询价

* Please select Quantity before adding items.

Customer Review

Other Forms of Levomilnacipran-d5 hydrochloride:

Levomilnacipran-d5 hydrochloride 相关抗体

Top Publications Citing Use of Products

查看 Trk Receptor 亚型特异性产品:

查看所有亚型
TrkA TrkB TrkC Trk

查看 PI3K 亚型特异性产品:

查看所有亚型
PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

查看 Akt 亚型特异性产品:

查看所有亚型
Akt Akt1 Akt2 Akt3

查看 mTOR 亚型特异性产品:

查看所有亚型
mTOR mTORC1 mTORC2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Levomilnacipran-d5 ((1S,2R)-Milnacipran-d5) hydrochloride is deuterium labeled Levomilnacipran hydrochloride (HY-B0168B). Levomilnacipran ((1S,2R)-Milnacipran) hydrochloride is the enantiomer of Milnacipran (HY-B0168) and a strong substrate of P-gp that can cross the blood-brain barrier. Levomilnacipran hydrochloride is a serotonin and norepinephrine reuptake inhibitor, with IC50 values of 10.5 nM and 19.0 nM, and Ki values of 92.2 nM and 1.2 nM for human norepinephrine transporter (NET) and serotonin transporter (SERT), respectively. Levomilnacipran hydrochloride has antidepressant and anxiolytic activities. Levomilnacipran hydrochloride can be used for the research of depression[1].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Levomilnacipran-d5 hydrochloride 相关抗体:
分子量

287.84

Formula

C15H18D5ClN2O
非标记 CAS
中文名称

左旋米那普林-d5 (盐酸盐)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Levomilnacipran-d5 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Levomilnacipran-d5(1S,2R)-Milnacipran-d5F-2695-d5左旋米那普林-d5 (盐酸盐)Isotope-Labeled CompoundsSerotonin TransporterTrk ReceptorPI3KAktmTORP-glycoprotein5-HTTSERTSLC6A4Tropomyosin related kinase receptor Phosphoinositide 3-kinasePKBProtein kinase BMammalian target of RapamycinP-gpPgpMultidrug resistance protein 1MDR1ATP-binding cassette sub-family B member 1ABCB1Cluster of differentiation 243CD243Inhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Levomilnacipran-d5 hydrochloride
目录号：
HY-B0168BS
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z