2. Cell Cycle/DNA Damage
  3. Antifolate
  4. MX-68

MX-68 是一种口服有效的抗叶酸剂。MX-68 能延长 MRL/lpr 小鼠的寿命、延迟蛋白尿发生并抑制血清尿素氮和胆固醇的升高。MX-68 也是一种抗风湿剂，对类风湿关节炎相关细胞有强效抗增殖作用且能抑制大鼠关节炎。MX-68 可用于自身免疫性肾病、类风湿关节炎等自身免疫疾病的研究。

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MX-68

MX-68 Chemical Structure

CAS No. : 156579-02-1

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MX-68 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MX-68 is an orally active antifolate agent. MX-68 can prolong the lifespan of MRL/lpr mice, delay the onset of proteinuria, and inhibit the elevation of serum blood urea nitrogen and cholesterol levels. MX-68 is also an anti-rheumatic agent, which exerts potent antiproliferative effects on rheumatoid arthritis-related cells and can inhibit arthritis in rats. MX-68 can be used in the research of autoimmune diseases such as autoimmune kidney disease and rheumatoid arthritis[1][2].

分子量

512.54

Formula

C22H24N8O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MX-68 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MX-68156579-02-1MX68MX 68AntifolateMRL/lpr miceautoimmune diseaseshuman synovial cells (hSC)human peripheral blood mononuclear cells (hPBMC)arthritisInhibitorinhibitorinhibit

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