2. Anti-infection
  3. Beta-lactamase Antibiotic Bacterial
  4. Nafcillin

Nafcillin 是一种抗生素，是可逆的 β-lactamase 抑制剂。Nafcillin 具有抗菌活性，可用于葡萄球菌感染的研究。

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Nafcillin

Nafcillin Chemical Structure

CAS No. : 147-52-4

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规格 是否有货
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Nafcillin 的其他形式现货产品:

Customer Review

Other Forms of Nafcillin:

Nafcillin 相关抗体

Top Publications Citing Use of Products

查看 Beta-lactamase 亚型特异性产品:

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Nafcillin, an antibiotic, is a reversible inhibitor of β-lactamase. Nafcillin exhibits bactericidal activity, and can be used for the research of staphylococcal infections[1][2][3][4].

IC50 & Target

β-lactam

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
CHO IC50
34.9 μM
Compound: Nafcillin
Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 mins
Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 mins
[PMID: 23344796]
体内研究
(In Vivo)

Nafcillin (100 mg/kg; s.c.) exhibits bactericidal activity against methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant S. aureus (MRSA), with MICs of 0.5 μg/mL and 64.0 μg/mL for S. aureus strains Xen-29 and Xen-1, respectively, in mice[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

414.47

Formula

C21H22N2O5S
CAS 号
中文名称

萘夫西林
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Nafcillin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nafcillin147-52-4萘夫西林Beta-lactamaseAntibioticBacterialβ-lactamasebactericidalantibioticmethicillin-susceptiblemethicillin-resistantstaphylococcalMRSAInhibitorinhibitorinhibit

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目录号：
HY-B0555
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