2. Others Metabolic Enzyme/Protease Neuronal Signaling MAPK/ERK Pathway Immunology/Inflammation GPCR/G Protein NF-κB Apoptosis
  3. Opioid Receptor NF-κB p38 MAPK Isotope-Labeled Compounds Reactive Oxygen Species (ROS) NO Synthase Toll-like Receptor (TLR) Apoptosis
  4. Nalmefene Sulfate-d3

Nalmefene Sulfate-d3 是 Nalmefene (HY-107744) 的氘代物。Nalmefene 是一种能透过血脑屏障的阿片受体调节剂，是 MOR 和 DOR 拮抗剂，也是 KOR 部分激动剂。Nalmefene 具有抗炎、神经保护的活性。Nalmefene 可用于减少酒精依赖性疾病的研究。

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Nalmefene Sulfate-d<sub>3</sub> Chemical Structure

Nalmefene Sulfate-d3 Chemical Structure

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Customer Review

Nalmefene Sulfate-d3 相关抗体

Top Publications Citing Use of Products

查看 Opioid Receptor 亚型特异性产品:

查看所有亚型
μ Opioid Receptor/MOR κ Opioid Receptor/KOR δ Opioid Receptor/DOR NOP Receptor/ORL1

查看 NF-κB 亚型特异性产品:

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NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

查看 p38 MAPK 亚型特异性产品:

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p38 MAPK p38α p38β MAPK13 p38δ p38γ

查看 NO Synthase 亚型特异性产品:

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nNOS iNOS eNOS

查看 Toll-like Receptor (TLR) 亚型特异性产品:

查看所有亚型
TLR3 TLR8 TLR9 TLR2 TLR4 TLR7 TLR1 TLR6

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Nalmefene Sulfate-d3 is the deuterium labeled Nalmefene (HY-107744). Nalmefene is a BBB-penetrable opioid receptor modulator. Nalmefene is an antagonist of MOR and DOR, and a partial agonist of KOR. Nalmefene has anti-inflammatory and neuroprotective activities. Nalmefene can be used in the research of reducing alcohol-dependent disorders[1][2][3][4].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Nalmefene Sulfate-d3 相关抗体:
分子量

422.51

Formula

C21H22D3NO6S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Nalmefene Sulfate-d3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Nalmefene Sulfate-d3Opioid ReceptorNF-κBp38 MAPKIsotope-Labeled CompoundsReactive Oxygen Species (ROS)NO SynthaseToll-like Receptor (TLR)ApoptosisNuclear factor-κBNuclear factor-kappaBNitric oxide synthasesNOSInhibitorinhibitorinhibit

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目录号：
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