2. Autophagy
  3. Autophagy
  4. Norswertianin

Norswertianin 是一种氧杂蒽酮类化合物，是一种有效的抗神经胶质瘤化合物 (anti-glioma compound)。Norswertianin 通过氧化应激和 Akt/mTOR 依赖的自噬诱导 GBM 细胞分化。

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Norswertianin Chemical Structure

Norswertianin Chemical Structure

CAS No. : 22172-15-2

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Norswertianin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Norswertianin, a xanthone compound, serves as a powerful anti-glioma compound. Norswertianin induces GBM cells differentiation through oxidative stress and Akt/mTOR dependent autophagy[1].

体外研究
(In Vitro)

Norswertianin (12.5-50 µM; 48 hours) stimulats expression of GFAP and β-tubulin in U251 cells[1].
Norswertianin (40 µM; 48 hours) causes the appearance of elongated processes in U251 cells, associated with G2/M cell cycle arrest[1].
Norswertianin (40 µM; 48 hours) exhibits an increase in intracellular acidification and LC3 conversion[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Norswertianin 相关抗体:
分子量

260.20

Formula

C13H8O6
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Norswertianin 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Norswertianin22172-15-2AutophagyantigliomaGBMdifferentiationglioblastomaautophagyInhibitorinhibitorinhibit

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