2. Anti-infection
  3. Bacterial Antibiotic
  4. Oxacillin

Oxacillin 是一种具有口服活性的合成青霉素，对葡萄球菌和其他革兰氏阳性病原体具有良好的杀菌 (bactericidal) 活性。

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Oxacillin

Oxacillin Chemical Structure

CAS No. : 66-79-5

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Oxacillin 的其他形式现货产品:

Customer Review

Other Forms of Oxacillin:

Oxacillin 相关抗体

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Oxacillin is an orally active synthetic penicillin with good bactericidal activity against staphylococci and other gram-positive pathogens[1].

IC50 & Target

β-lactam

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
CHO IC50
35 μM
Compound: Oxacillin
Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 mins
Inhibition of mouse OAT3 expressed in CHO cells assessed as inhibition of fluorescein uptake over 20 mins
[PMID: 23344796]
体外研究
(In Vitro)

Oxacillin inhibits gram positive pathogens with MICs of 0.05, 0.09, 0.32 and 0.80 μg/mL against group A streptococci, Pneutnococci, susceptible staphylococci and penicillin-resistant staphylococci, respectively[1].
The Oxacillin-resistant strains are highly resistant to other penicillins[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Oxacillin 相关抗体:
体内研究
(In Vivo)

Oxacillin (50-800 mg/kg; s.c.; once) shows curative dose (CD50) of 253.3 mg/kg in mice infected with Staphylococcus aureus Evans. The oral CD50 of Oxacillin is 187.2 mg/kg[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: CD-1 strain male albino mice infected with S. aureus Evans[2]
Dosage: 50, 100, 200, 400 and 800 mg/kg
Administration: Subcutaneous injection, once
Result: Showed therapeutic activity with CD50 of 253.3 mg/kg.
Clinical Trial
分子量

401.44

Formula

C19H19N3O5S
CAS 号
中文名称

苯唑西林
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Oxacillin 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Oxacillin66-79-5苯唑西林BacterialAntibioticorally activestaphylococcigram-positive pathogensStaphylococcus aureusInhibitorinhibitorinhibit

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