2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. PDE4-IN-13

PDE4-IN-13 是一种 PDE4 抑制剂，IC50 为 1.56 μM。PDE4-IN-13具有抗炎和抗氧化特性，可用于慢性阻塞性肺疾病（COPD）研究。

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PDE4-IN-13 Chemical Structure

PDE4-IN-13 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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100 mg   询价  
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Customer Review

PDE4-IN-13 相关抗体

Top Publications Citing Use of Products

查看 Phosphodiesterase (PDE) 亚型特异性产品:

查看所有亚型
PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PDE4-IN-13 is a PDE4 inhibitor with an IC50 of 1.56 μM. PDE4-IN-13 shows anti-inflammatory and antioxidant properties， and can be used for chronic obstructive pulmonary disease (COPD) research[1].

IC50 & Target[1]

PDE4

1.56 μM (IC50)

体外研究
(In Vitro)

PDE4-IN-13（化合物 6o）可减少 RAW264.7 巨噬细胞中脂多糖 (LPS) 诱导的 TNF-α 产生以及小鼠肺匀浆中 Fe2+ 诱导的丙二醛 (MDA) 产生。同时，PDE4-IN-13 在还原 Fe3+ 和络合 Fe2+ 方面表现出优异的能力[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

PDE4-IN-13 相关抗体:
体内研究
(In Vivo)

PDE4-IN-13（化合物 6o）（50 mg/kg 和 100 mg/kg，腹膜内注射）可明显预防 LPS 诱导的小鼠血清 TNF-α 水平[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

340.37

Formula

C20H20O5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PDE4-IN-13 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PDE4-IN-13Phosphodiesterase (PDE)antioxidant propertiesanti-inflammatoryTNF-αchronic obstructive pulmonary diseasePDE4 inhibitorInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-155692
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