1. PROTAC
  2. PROTAC Linker
  3. PROTAC Linker 30

PROTAC Linker 30 

目录号: HY-125887
产品使用指南

PROTAC Linker 30 是一种 PROTAC 连接桥,属于 alkyl/ether 类。PROTAC Linker 30 可用于合成一系列 PROTAC 分子。PROTAC 分子含有两个通过连接桥连接的不同配体; 一种是 E3 泛素连接酶配体,另一种是靶蛋白配体。PROTAC 利用细胞内泛素-蛋白酶体系统选择性降解靶蛋白。

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PROTAC Linker 30 Chemical Structure

PROTAC Linker 30 Chemical Structure

CAS No. : 1310327-20-8

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Description

PROTAC Linker 30 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 30 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC50 & Target

Alkyl/ether

 

Molecular Weight

376.45

Formula

C₁₇H₃₂N₂O₇

CAS No.

1310327-20-8

SMILES

O=C(OC(C)(C)C)NCCOCCOCCNC(CCCCC(O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
PROTAC Linker 30
目录号:
HY-125887
需求量:

PROTAC Linker 30

Cat. No.: HY-125887