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  4. ABCB5 蛋白, Human (Trx)

ABCB5 蛋白, Human (Trx)

目录号: HY-P7621
产品使用指南

ABCB5, N-Trx 蛋白, Human是一种由 ABCB5 基因编码的跨膜蛋白。ABCB5 是 ABC 转运蛋白和 P-糖蛋白家族成员，主要在生理性皮肤和人类恶性黑色素瘤中表达。

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规格 是否有货
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100 μg   询价  

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描述

ABCB5, N-Trx Protein, Human is a plasma membrane-spanning protein that in humans is encoded by the ABCB5 gene. ABCB5 is an ABC transporter and P-glycoprotein family member principally expressed in physiological skin and human malignant melanoma[1].
研究背景

ATP 结合盒 (ABC) 转运蛋白在生理学和病理学中发挥着关键作用。ABCB5α/β的表达可能为黑色素瘤的鉴别诊断提供两种新的分子标志物，并成为黑色素瘤治疗的潜在分子靶点[1]。
种属

Human
表达系统

E. coli
标签

N-Trx
蛋白编号

Q2M3G0 (I586-V692)
基因 ID
蛋白结构
N-term
Trx
ABCB5 (I586-V692)
Accession # Q2M3G0
C-term
同用名
rHuABCB5, N-Trx; ATP-binding cassette sub-family B member 5; P-glycoprotein ABCB5; ABCB5
氨基酸序列

IRSADLIVTLKDGMLAEKGAHAELMAKRGLYYSLVMSQDIKKADEQMESMTYSTERKTNSLPLHSVKSIKSDFIDKAEESTQSKEISLPEVSLLKILKLNKPEWPFV

分子量

Approximately 30.0 kDa
纯度

Greater than 85% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)
参考文献

ABCB5 Protein, Human (Trx) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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