1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. RECTAS-2.0

RECTAS-2.0 是一种小分子,旨在纠正由 GLA c.639+919G>A 突变引起的 RNA 错误剪接,用于法布里病的研究。

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RECTAS-2.0 Chemical Structure

RECTAS-2.0 Chemical Structure

CAS No. : 3038234-95-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

RECTAS-2.0 is a small molecule designed to correct RNA mis-splicing caused by the GLA c.639+919G>A mutation, used for the research of Fabry disease[1].

体外研究
(In Vitro)

RECTAS-2.0 能够在源自患者的B淋巴母细胞系和诱导的多能干细胞来源的心肌细胞中恢复正常的 GLA mRNA 剪接和 α-半乳糖苷酶活性[1]
RECTAS-2.0 显示出在其他涉及类似外显子竞争的遗传性疾病中也具有潜在的应用可能性[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

388.80

Formula

C18H17ClN4O4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
RECTAS-2.0
目录号:
HY-172552
需求量: