1. PROTAC
  2. E3 Ligase Ligand-Linker Conjugate
  3. (S,R,S)-AHPC-C7-amine

(S,R,S)-AHPC-C7-amine (Synonyms: VH032-C7-amine)

目录号: HY-136186
产品使用指南

(S,R,S)-AHPC-C7-amine (VH032-C7-amine) 是一种合成的 E3 连接酶配体-linker (E3 ligase ligand-linker conjugate) 偶联物,包含基于 VH032 的 VHL 配体和 1 个 linker。(S,R,S)-AHPC-C7-amine 可用于合成靶向 ERRα 的 PROTAC 降解剂。

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(S,R,S)-AHPC-C7-amine Chemical Structure

(S,R,S)-AHPC-C7-amine Chemical Structure

CAS No. : 2306389-04-6

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Description

(S,R,S)-AHPC-C7-amine (VH032-C7-amine) is a synthesized E3 ligase ligand-linker conjugate that incorporates the VH032 based VHL ligand and a linker used for estrogen-related receptor α (ERRα) PROTAC degrader[1].

IC50 & Target[1]

VHL

 

Molecular Weight

571.77

Formula

C₃₀H₄₅N₅O₄S

CAS No.

2306389-04-6

SMILES

O=C([C@H]1N(C([C@@H](NC(CCCCCCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

(S,R,S)-AHPC-C7-amineVH032-C7-amineE3 Ligase Ligand-Linker ConjugateERRαPROTACVH032Inhibitorinhibitorinhibit

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产品名称:
(S,R,S)-AHPC-C7-amine
目录号:
HY-136186
需求量: