2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. (S)-SCH-23390 hydrochloride

(S)-SCH-23390 hydrochloride  (Synonyms: SCH-23388 hydrochloride)

目录号: HY-19545B
产品使用指南 技术支持

(S)-SCH-23390 (hydrochloride) 是 SCH-23390 (HY-19545) 的 S- 对映异构体。SCH-23390 是一种多巴胺 D1 样受体 (D1-like receptor) 拮抗剂 (对 D1 和 D5 受体亚型的 Ki 值分别为 0.2 nM 和 0.3 nM)。

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(S)-SCH-23390 hydrochloride

(S)-SCH-23390 hydrochloride Chemical Structure

CAS No. : 1217443-99-6

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规格 价格 是否有货 数量
5 mg ￥690
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10 mg ￥990
In-stock
25 mg ￥2070
In-stock
50 mg ￥3780
In-stock
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Other Forms of (S)-SCH-23390 hydrochloride:

(S)-SCH-23390 hydrochloride 相关抗体

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Dopamine Receptor D1 Receptor D2 Receptor D3 Receptor D4 Receptor D5 Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(S)-SCH-23390 (hydrochloride) is the S-enantiomer of SCH-23390 (HY-19545). SCH-23390 is a dopamine D1-like receptor antagonist (with Ki values of 0.2 nM and 0.3 nM for the D1 and D5 receptor subtypes, respectively)[1].

体内研究
(In Vivo)

(S)-SCH-23390 (0.05-15.5 mg/kg，腹腔注射，单次给药) (hydrochloride) 未显著减少大鼠的脑脊液 (CSF) 净生成量[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male SD rats (140-200 g)[1]
Dosage: 0.05, 0.5, 5.0 and 15.5 mg/kg
Administration: i.p., single dose
Result: Did not significantly reduce the net production of CSF at any dose between 0.05 and 15.5 mg/kg.
分子量

324.24

Formula

C17H19Cl2NO
CAS 号
性状

粉末

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

(S)-SCH-23390 hydrochloride 相关分类

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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-SCH-233901217443-99-6SCH-23388SCH23388SCH 23388Dopamine ReceptorS-enantiomerCSFratSCH-23390Inhibitorinhibitorinhibit

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