2. Immunology/Inflammation
  3. CD28 CD38 CD3
  4. SAR-442257

SAR442257 是一种靶向多发性骨髓瘤细胞表面 CD38 与 CD28 的人源化 IgG4-S228P（κ型）单克隆抗体，同时可共刺激 T 细胞的 CD3 与 CD28 分子。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥3000
In-stock
5 mg ￥9000
In-stock
10 mg ￥14500
In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

SAR-442257 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SAR442257 is a humanized IgG4-S228P, kappa monoclonal antibody targeting CD38 and CD28 on multiple myeloma cells and co-stimulates CD3 and CD28 on T cells[1].

同型

Human IgG4 kappa
推荐同型对照抗体
反应种属

Human
IC50 & Target

CD28 & CD38
Clinical Trial
基因 ID

940  [NCBI] & 952  [NCBI]

Accession
应用

ELISA, FACS, Functional assay
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
  • Immobilized CD28-mFC can bind SAR-442257. The EC50 for this effect is 300.8 ng/mL.
纯度 & 产品资料
参考文献

SAR-442257 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SAR-442257SAR442257SAR 442257CD28CD38CD3Cluster of differentiation 3multiple myelomaInhibitorinhibitorinhibit

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Inquiry Information

产品名称：
SAR-442257
目录号：
HY-P991183
需求量：

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