2. Anti-infection
  3. SARS-CoV
  4. SARS-CoV-2 nsp13-IN-4

SARS-CoV-2 nsp13-IN -4 (C4 (d)) 是一种强效的选择性 nsp13 helicase 小分子抑制剂，可抑制 nsp13 的 ssDNA+ ATPase 活性，其 IC50 值为57 μM。SARS-CoV-2 nsp13-IN-4 为类活性分子分子，分子量小于450 Da，具有广谱抗 病毒 作用。

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SARS-CoV-2 nsp13-IN-4 Chemical Structure

SARS-CoV-2 nsp13-IN-4 Chemical Structure

CAS No. : 923140-39-0

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SARS-CoV-2 nsp13-IN-4 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SARS-CoV-2 nsp13-IN-4 (C4 (d)) is a potent and selective nsp13 helicase small-molecule inhibitor and inhibit the ssDNA+ ATPase activity of nsp13 with an IC50 value of 57 μM. SARS-CoV-2 nsp13-IN-4 is agentlike molecule with molecular weight of less than 450Da and can provide a broad-spectrum antiviral effect[1].

IC50 & Target

IC50: 57 μM (nsp13 ssDNA+ ATPase) [1]
体外研究
(In Vitro)

SARS-CoV-2 nsp13-IN-4 (C4 (d)) inhibits the ssDNA+ ATPase activity and the ssDNA− ATPase activity of nsp13 with IC50 values of 57 μM and 240 μM, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

SARS-CoV-2 nsp13-IN-4 相关抗体:
分子量

407.26

Formula

C20H15BrN4O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SARS-CoV-2 nsp13-IN-4 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SARS-CoV-2 nsp13-IN-4923140-39-0SARS-CoVSARS coronavirusnsp13 small-molecule inhibitorantiviralinfectionInhibitorinhibitorinhibit

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