2. Others Neuronal Signaling
  3. α-synuclein Isotope-Labeled Compounds Amyloid-β
  4. Scyllo-Inositol-d6

Scyllo-Inositol-d6  (Synonyms: 鲨肌醇-d6)

目录号: HY-W707693
产品使用指南 技术支持

Scyllo-Inositol-d6 是 Scyllo-Inositol (HY-W010041) 的氘代物。Scyllo-Inositol 是一种靶向错误折叠蛋白质 (如 α-synuclein、Amyloid-β) 聚集的抑制剂，具有口服有效性且能通过血脑屏障。Scyllo-Inositol 可选择性结合并稳定非毒性寡聚体，阻止其转化为有毒纤维，发挥蛋白质稳态调节作用和神经元保护活性。Scyllo-Inositol 与致病蛋白的疏水区结合，抑制蛋白质聚集、促进溶酶体和蛋白酶体介导的降解途径，从而减轻神经毒性。Scyllo-Inositol 可用于帕金森病、阿尔茨海默病及亨廷顿病等神经退行性疾病的研究。

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Scyllo-Inositol-d<sub>6</sub>

Scyllo-Inositol-d6 Chemical Structure

CAS No. : 115268-26-3

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Other Forms of Scyllo-Inositol-d6:

Scyllo-Inositol-d6 相关抗体

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α-synuclein α-synuclein Aggregation α-synuclein/CHMP2B

  • 生物活性

  • 纯度 & 产品资料

生物活性

Scyllo-Inositol-d6 is the deuterium labeled Scyllo-Inositol (HY-W010041). Scyllo-Inositol is an inhibitor that targets the aggregation of misfolded proteins (such as α-synuclein and Amyloid-β), is orally effective, and can cross the blood-brain barrier. Scyllo-Inositol can selectively bind to and stabilize non-toxic oligomers, preventing them from converting into toxic fibers, exerting protein homeostasis regulation and neuroprotective activity. Scyllo-Inositol binds to the hydrophobic region of pathogenic proteins, inhibits protein aggregation, and promotes lysosome- and proteasome-mediated degradation pathways, thereby reducing neurotoxicity. Scyllo-Inositol can be used in the study of neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, and Huntington's disease[1][2][3].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Scyllo-Inositol-d6 相关抗体:
分子量

186.19

Formula

C6H6D6O6
CAS 号
非标记 CAS
中文名称

鲨肌醇-d6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Scyllo-Inositol-d6 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Scyllo-Inositol-d6115268-26-3鲨肌醇-d6α-synucleinIsotope-Labeled CompoundsAmyloid-βα-Synβ-amyloid peptideAβAbetaInhibitorinhibitorinhibit

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