1. Apoptosis NF-κB
  2. TNF Receptor NF-κB Apoptosis
  3. TNF-α (31-45), human TFA

TNF-α (31-45), human TFA 是一种有效的 NF-kB 通路激活剂,也是一种促炎细胞因子,可诱导坏死或凋亡。TNF α 通过 TNFR2 刺激 NF-κB 通路,促进癌症生长、侵袭和转移。

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Custom Peptide Synthesis

TNF-α (31-45), human TFA Chemical Structure

TNF-α (31-45), human TFA Chemical Structure

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规格 价格 是否有货
1 mg ¥750
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5 mg ¥1850
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10 mg ¥3000
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TNF-α (31-45), human TFA 的其他形式现货产品:

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Top Publications Citing Use of Products

查看 NF-κB 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TNF-α (31-45), human TFA is a potent NF-kB pathway activator. TNF-αis a proinflammatory cytokine that induces necrosis or apoptosis. TNF alpha stimulates NF-κB pathway via TNFR2 promotes cancer growth, invasion, and metastasis[1][2][3].

IC50 & Target[1][2]

NF-κB

 

体外研究
(In Vitro)

TNF-α (31-45), human (5 μM;持续 1 小时) TFA 通过激活 NF-kB 途径促进顺铂耐药。TNF-α (31-45),人类不会改变 RPS3 表达水平[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1667.87 (free acid)

Formula

C69H122N26O22.xC2HF3O2

性状

固体

颜色

White to off-white

Sequence Shortening

RRANALLANGVELRD

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料
参考文献

TNF-α (31-45), human TFA 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
TNF-α (31-45), human TFA
目录号:
HY-P1860A
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