2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Trimazosin

Trimazosin  (Synonyms: 曲马唑嗪；三甲氧唑啉；三甲哌唑嗪)

目录号: HY-106554
产品使用指南

摩尔计算器

Trimazosin 是一种具有口服活性的 quinazoline 衍生物，其结构与 prazosin 有关。Trimazosin 通过选择性阻断α1肾上腺素受体 (α1-adrenoceptors) 表现出降压 (hypotensive) 作用。

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Trimazosin Chemical Structure

Trimazosin Chemical Structure

CAS No. : 35795-16-5

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Trimazosin 相关抗体

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查看 Adrenergic Receptor 亚型特异性产品:

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α adrenergic receptor β adrenergic receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Trimazosin is an orally active, quinazoline derivative which is structurally related to prazosin. Trimazosin shows hypotensive effect by selectively block α1-adrenoceptors[1][2].

IC50 & Target

α1-adrenergic receptor

 

体内研究
(In Vivo)

Trimazosin (10–30 mg/kg; i.h.; once) produces graded decreases in blood pressure[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Conscious spontaneously hypertensive rats (SHR)[3]
Dosage: 10–30 mg/kg
Administration: Subcutaneous administration, once
Result: Produced graded decreases in blood pressure.
分子量

435.47

Formula

C20H29N5O6
CAS 号
中文名称

曲马唑嗪；三甲氧唑啉；三甲哌唑嗪
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Trimazosin 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Trimazosin35795-16-5曲马唑嗪三甲氧唑啉三甲哌唑嗪Adrenergic ReceptorBeta ReceptorQuinazoline derivativePrazosinHypotensive effectInhibitorinhibitorinhibit

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