2. Apoptosis
  3. Apoptosis
  4. Visilizumab

Visilizumab  (Synonyms: Anti-Human CD3E Recombinant Antibody; HuM291)

目录号: HY-P99332 纯度: 98.43%
COA

摩尔计算器

Visilizumab (Anti-Human CD3E Recombinant Antibody) 是一种人源化低 Fc 受体结合抗 CD3 单克隆 IgG2 抗体。Visilizumab 可用于溃疡性结肠炎和克罗恩病的研究。

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Visilizumab Chemical Structure

Visilizumab Chemical Structure

CAS No. : 219716-33-3

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规格 价格 是否有货 数量
1 mg ￥3000
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5 mg ￥9500
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Visilizumab 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Visilizumab (Anti-Human CD3E Recombinant Antibody) is a humanized low-Fc receptor binding anti-CD3 monoclonal IgG2 antibody. Visilizumab can be used for ulcerative colitis and Crohn's disease research[1].

体外研究
(In Vitro)

Visilizumab 诱导固有层 T 细胞的剂量和时间依赖性细胞凋亡。Visilizumab 诱导固有层 T 细胞凋亡依赖于半胱天冬酶 3 和 8，而不是半胱天冬酶 9 的激活，并且不涉及 Fas/FasL 通路[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Visilizumab 相关抗体:

Apoptosis Analysis[1]

Cell Line: Lamina propria T cells
Concentration: 1 ng/mL, 10 ng/mL, 100 ng/mL, 1000 ng/mL, 10000 ng/mL
Incubation Time: 2 hours, 4 hours, 20 hours, 24 hours, 48 hours
Result: Induced dose- and time-dependent apoptosis of lamina propria T cells.
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

维西珠单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Visilizumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Visilizumab219716-33-3Anti-Human CD3E Recombinant Antibody HuM291维西珠单抗HuM291HuM 291HuM-291ApoptosisCD3low-Fc receptormonoclonal IgG2 antibodyulcerative colitisCrohn's diseaseInhibitorinhibitorinhibit

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