Xanthine-¹³C,¹⁵N₂  (Synonyms: 黄嘌呤-¹³C,¹⁵N₂)

Xanthine-¹³C,¹⁵N₂ is a ¹⁵N-labeled and ¹³C-labled Xanthine (HY-W017389). Xanthine is a plant alkaloid with mild stimulant activity of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation^[1][2][3].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[75].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

155.09

C₄¹³CH₄N₂¹⁵N₂O₂

1262670-81-4

固体

White to off-white

黄嘌呤-¹³C,¹⁵N₂

Room temperature in continental US; may vary elsewhere.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-244.  [Content Brief]

  [2]. Pundir CS, et al. Biosensing methods for xanthine determination: a review. Enzyme Microb Technol. 2014;57:55-62.  [Content Brief]

  [3]. David A. Taylor, et al. Central Nervous SystemStimulants.