2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 2-Methyl estradiol

2-Methyl estradiol 是雌二醇 (HY-B0141) 的内源性代谢物，能抑制细胞增殖和血管生成，对 HUVEC (人脐静脉内皮细胞) 和 MCF-7 (人乳腺癌细胞) 的增殖的 IC50 值分别为 3 μM 和 2.39 μM。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

2-Methyl estradiol

2-Methyl estradiol Chemical Structure

CAS No. : 1818-12-8

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

2-Methyl estradiol 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2-Methyl estradiol, an endogenous metabolite of Estradiol (HY-B0141), inhibits cell proliferation and angiogenesis, with IC50 values of 3 and 2.39 μM for HUVEC and MCF-7 human breast cancer cell proliferation, respectively[1].
细胞效力
(Cellular Effect)
Cell Line Type Value Description References
DU-145 GI50
16 μM
Compound: 9
Cytotoxicity against prostate DU-145 cancer cell lines.
Cytotoxicity against prostate DU-145 cancer cell lines.
[PMID: 7783135]
DU-145 GI50
51 μM
Compound: 8
Antiproliferative activity against human DU145 cells after 96 hrs by WST1 assay
Antiproliferative activity against human DU145 cells after 96 hrs by WST1 assay
[PMID: 17696419]
HCT-116 GI50
3.6 μM
Compound: 9
Cytotoxicity against colon HCT116 cancer cell lines.
Cytotoxicity against colon HCT116 cancer cell lines.
[PMID: 7783135]
HOP-62 GI50
11 μM
Compound: 9
Cytotoxicity against lung HOP-62 cancer cell lines.
Cytotoxicity against lung HOP-62 cancer cell lines.
[PMID: 7783135]
MDA-MB-435 GI50
1.8 μM
Compound: 9
Cytotoxicity against breast MDA-MB-435 cancer cell lines.
Cytotoxicity against breast MDA-MB-435 cancer cell lines.
[PMID: 7783135]
OVCAR-3 GI50
9.1 μM
Compound: 9
Cytotoxicity against ovarian OVCAR-3 cancer cell lines.
Cytotoxicity against ovarian OVCAR-3 cancer cell lines.
[PMID: 7783135]
Panel (Carcinoma cell lines) GI50
8.1 μM
Compound: 9
Mean graph midpoint for all human cancer cell line cytotoxicity.
Mean graph midpoint for all human cancer cell line cytotoxicity.
[PMID: 7783135]
SF-539 GI50
7.4 μM
Compound: 9
Cytotoxicity against CNS SF-539 cancer cell lines.
Cytotoxicity against CNS SF-539 cancer cell lines.
[PMID: 7783135]
SN12C GI50
17 μM
Compound: 9
Cytotoxicity against renal SN12C cancer cell lines.
Cytotoxicity against renal SN12C cancer cell lines.
[PMID: 7783135]
UACC-62 GI50
5.4 μM
Compound: 9
Cytotoxicity against melanoma UACC-62 cancer cell lines.
Cytotoxicity against melanoma UACC-62 cancer cell lines.
[PMID: 7783135]
分子量

286.41

Formula

C19H26O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

2-Methyl estradiol 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Methyl estradiol1818-12-8Endogenous MetaboliteHUVECMCF-7EstradiolInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
2-Methyl estradiol
目录号：
HY-W702106
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z