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  3. 2E-3-F16

2E-3-F16 是一种抗癌剂。2E-3-F16 在 NCI-H446 癌细胞和 HBE 细胞之间表现出肿瘤细胞选择性。2E-3-F16 增强 A549 细胞对 Cisplatin (HY-17394) 的敏感性。

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2E-3-F16

2E-3-F16 Chemical Structure

CAS No. : 3002962-69-5

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  • 生物活性

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生物活性

2E-3-F16 is a anticancer agent. 2E-3-F16 exhibits tumor cell selectivity between NCI-H446 cancer cells and HBE cells. 2E-3-F16 enhances the sensitivity of A549 cells to Cisplatin (HY-17394)[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
4.6 μM
Compound: 2E-3-F16
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 38086195]
HepG2 IC50
2.48 μM
Compound: 2E-3-F16
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 38086195]
L02 IC50
2.62 μM
Compound: 2E-3-F16
Cytotoxicity against human HL7702 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HL7702 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 38086195]
NCI-H446 IC50
2.87 μM
Compound: 2E-3-F16
Antiproliferative activity against human NCI-H446 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Antiproliferative activity against human NCI-H446 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 38086195]
分子量

649.66

Formula

C39H41BrN2O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
2E-3-F16
目录号:
HY-157292
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