2. Anti-infection Metabolic Enzyme/Protease
  3. EBV HIV Protease HSV
  4. 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid

2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid 

目录号: HY-N4155
产品使用指南

摩尔计算器

2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid 是一种天然的熊烷型三萜，是一种有效的 HIV 蛋白酶 (HIV protease) (HIV Protease) 抑制剂。2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid 也是 Epstein-Barr 病毒早期抗原 (EBV-EA) 激活的抑制剂。2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid 对脂多糖 (Lipopolysaccharides) 激活的 RAW 264.7 细胞中的一氧化氮产生具有抑制活性。

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2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid Chemical Structure

2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid Chemical Structure

CAS No. : 176983-21-4

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2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid, a natural ursane-type triterpene, is a potent inhibitor of HIV protease (HIV Protease). 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid is also an inhibitor of the activation of Epstein-Barr virus early antigen (EBV-EA). 2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid displays an inhibitory activity against nitric oxide production in Lipopolysaccharide (Lipopolysaccharides)-activated RAW 264.7 cells[1][2].

体外研究
(In Vitro)

2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid (0.01-0.1 μM) 在脂多糖激活的巨噬细胞系、RAW 264.7 细胞中显示出对一氧化氮产生的中等抑制活性[1 ]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid 相关抗体:
体内研究
(In Vivo)

2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid (0.0025%；饮用水；20 周) 显示出对 TPA 诱导的 EBV-EA 激活的抑制作用，并导致显着延迟 小鼠皮肤两阶段癌变[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female ICR mice (6 weeks old)[2]
Dosage: 0.0025%
Administration: Drinking water; for 20 weeks
Result: Showed an inhibitory effect on the activation of EBV-EA induced by 12-O-tetradecanoylphorbol-13-acetate (TPA).
分子量

486.68

Formula

C30H46O5
CAS 号
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid 相关分类

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Keywords:

2α,19α-Dihydroxy-3-oxo-urs-12-en-28-oic acid176983-21-4EBVHIV ProteaseHSVEpstein-Barr VirusHerpes simplex virusanti-HIV activityanti-initiating agentEBV-EAtriterpeneHIV proteasenitric oxideInhibitorinhibitorinhibit

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