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  4. 4-Formylcolchicine

4-Formylcolchicine 是一种有效的抗癌剂，能够与乳糖化血清白蛋白结合发挥抗纤维化作用。4-Formylcolchicine 显示细胞毒性活性，对 A549、HT-29、HCT116 细胞的 IC50 值分别为 1.007、0.128、0.054 μM。

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4-Formylcolchicine

4-Formylcolchicine Chemical Structure

CAS No. : 2730-82-7

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规格 价格 是否有货
5 mg ￥950
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10 mg ￥1650
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25 mg ￥3450
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50 mg ￥5500
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100 mg 询价 询问价格 & 货期

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4-Formylcolchicine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

4-Formylcolchicine is a potent anticancer agent. 4-Formylcolchicine shows cytotoxicity activity with IC50 values of 1.007, 0.128, 0.054 μM for A549, HT-29, HCT116 cells, respectively[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
1.007 μM
Compound: 7
Cytotoxicity against human A549 cells after 96 hrs using tetracolor one
Cytotoxicity against human A549 cells after 96 hrs using tetracolor one
[PMID: 24900316]
HCT-116 IC50
0.054 μM
Compound: 7
Cytotoxicity against human HCT116 cells after 96 hrs using tetracolor one
Cytotoxicity against human HCT116 cells after 96 hrs using tetracolor one
[PMID: 24900316]
HT-29 IC50
0.128 μM
Compound: 7
Cytotoxicity against human HT-29 cells after 96 hrs using tetracolor one
Cytotoxicity against human HT-29 cells after 96 hrs using tetracolor one
[PMID: 24900316]
体外研究
(In Vitro)

4-Formylcolchicine (compound 7) (0-5 μM; 24 h) shows antiproliferative activity with IC50s of 1.007, 0.128, 0.054 μM for A549, HT-29, HCT116 cells, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

4-Formylcolchicine 相关抗体:

Cell Viability Assay[1]

Cell Line: A549, HT-29, HCT116 cells
Concentration: 0-5 µM
Incubation Time: 24 h
Result: Inhibited cell growth with IC50s of 1.007, 0.128, 0.054 µM for A549, HT-29, HCT116 cells, respectively.
分子量

427.45

Formula

C23H25NO7
CAS 号
性状

固体

颜色

Light yellow to yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料
参考文献

4-Formylcolchicine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-Formylcolchicine2730-82-7Biochemical Assay ReagentsInhibitorinhibitorinhibit

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目录号：
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