1. Cell Cycle/DNA Damage Cytoskeleton Apoptosis
  2. Microtubule/Tubulin Apoptosis
  3. 6-MOMIPP

6-MOMIPP 是一种可穿透血脑屏障的微管 (microtubule) 破坏剂,靶向 β-微管蛋白 (β-tubulin) 上的秋水仙碱结合位点。6-MOMIPP 能够诱导有丝分裂停滞和细胞凋亡 (apoptosis)。6-MOMIPP 对多种胶质母细胞瘤、黑色素瘤和肺癌细胞系的活力具有广泛的抑制活性。6-MOMIPP 可用于癌症研究。

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6-MOMIPP

6-MOMIPP Chemical Structure

CAS No. : 1961272-45-6

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

6-MOMIPP is a brain-penetrant microtubule disruptor that targets the colchicine site on β-tubulin. 6-MOMIPP can induce mitotic arrest and cell apoptosis. 6-MOMIPP has broad activity against the viability of multiple glioblastoma, melanoma and lung carcinoma cell lines. 6-MOMIPP can be used for the research of cancer[1].

分子量

292.33

Formula

C18H16N2O2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
6-MOMIPP
目录号:
HY-115458
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