2. Neuronal Signaling GPCR/G Protein Metabolic Enzyme/Protease
  3. Adrenergic Receptor Endogenous Metabolite
  4. Octopamine

Octopamine 是一种与去甲肾上腺素结构相关的生物单胺类物质，在无脊椎动物中起着神经激素、神经调节剂和神经递质的作用。Octopamine 对转染人 alpha2-肾上腺素受体 (ARs) 的中国仓鼠卵巢细胞 α2-ARs 有刺激作用。Octopamine 增加糖原分解、糖酵解、摄氧量、糖异生和门脉灌注压。

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Octopamine

Octopamine Chemical Structure

CAS No. : 104-14-3

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Octopamine 的其他形式现货产品:

Other Forms of Octopamine:

Octopamine 相关抗体

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α adrenergic receptor β adrenergic receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Octopamine is a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. Octopamine can stimulate alpha2-adrenoceptors (ARs) in Chinese hamster ovary cells transfected with human alpha2-ARs. Octopamine increased glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis and the portal perfusion pressure[1][2][3].

IC50 & Target

Human Endogenous Metabolite

 

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK293 EC50
24 nM
Compound: octopamine
Activity at SER3 receptor expressed in HEK293 cells assessed as increase in calcium by calcium imaging assay
Activity at SER3 receptor expressed in HEK293 cells assessed as increase in calcium by calcium imaging assay
[PMID: 18033297]
分子量

153.18

Formula

C8H11NO2
CAS 号
性状

固体

颜色

White to off-white

中文名称

章胺； 章鱼胺
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

Octopamine 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Octopamine104-14-3章胺 章鱼胺Adrenergic ReceptorEndogenous MetaboliteBeta Receptorα-synucleinneurohormoneinvertebrateInhibitorinhibitorinhibit

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