1. Immunology/Inflammation
  2. PD-1/PD-L1
  3. Abazistobart

Abazistobart是一种免疫刺激剂和抗肿瘤剂,靶向程序性细胞死亡蛋白 1 (PDCD1)。Abazistobart 是一种嵌合人源化单克隆抗体,特异性结合 PDCD1 阻断相关信号通路,从而激活免疫系统,发挥抗肿瘤活性。Abazistobart 有望用于癌症的研究。

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CAS No. : 3002062-67-8

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     可免费申领三个不同产品的试用装。

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Abazistobart is an immunostimulant and antineoplastic agent targeting the programmed cell death protein 1 (PDCD1). Abazistobart is a chimeric and humanized monoclonal antibody that specifically binds to PDCD1 to block the relevant signaling pathway, thereby activating the immune system and exerting antineoplastic activity. Abazistobart is promising for research of cancers[1].

同型

Human IgG4 kappa

推荐同型对照抗体
反应种属

Human

IC50 & Target

PDCD1/PD-1/CD279

基因 ID

5133  [NCBI]

Accession
应用

ELISA, FACS, Functional assay

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • IgG4-kappa
纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
Abazistobart
目录号:
HY-P991113
需求量: