2. Others GPCR/G Protein Neuronal Signaling Immunology/Inflammation Anti-infection
  3. Reference Standards Histamine Receptor HBV
  4. Antazoline hydrochloride (Standard)

Antazoline hydrochloride (Standard)  (Synonyms: 盐酸安他唑啉 (Standard); Phenazoline hydrochloride (Standard))

目录号: HY-B1067R 纯度: ≥98%
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Antazoline (hydrochloride) (Standard) 是 Antazoline (hydrochloride) 的分析标准品。本产品用于研究及分析应用。Antazoline hydrochloride 是一种组胺 H1 受体拮抗剂 (histamine H1 receptor)，具有抗胆碱能和抗病毒作用。Antazoline hydrochloride 通过可逆性竞争作用于靶细胞的组胺受体位点，阻止组胺作用于靶细胞。Antazoline hydrochloride 啉通过阻断和抑制H1受体，发挥抗过敏作用，防止生理反应的发生。Antazoline hydrochloride 能剂量依赖性地有效降低细胞外上清液中的 HBV DNA，在 HepAD38 细胞中的 EC50 为 2.910 μmol/L。Antazoline hydrochloride 对 Huh7 细胞外上清液中的 HBV DNA 也有显著的抑制作用 (EC50 = 2.349 μmol/L)。Antazoline hydrochloride 对急性心肌梗死具有抗心律失常作用。Antazoline hydrochloride 可用于心血管疾病和乙型肝炎 (HBV) 的研究。

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Antazoline hydrochloride (Standard) Chemical Structure

Antazoline hydrochloride (Standard) Chemical Structure

CAS No. : 2508-72-7

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规格 价格 是否有货 数量
10 mg ￥328
3-5 周
25 mg ￥656
3-5 周
50 mg ￥1049
3-5 周
100 mg ￥1679
3-5 周
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

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生物活性

Antazoline (hydrochloride) (Standard) is the analytical standard of Antazoline (hydrochloride). This product is intended for research and analytical applications. Antazoline hydrochloride is a histamine H1 receptor antagonist with anticholinergic and antiviral properties. Antazoline hydrochloride can prevent histamine from acting on target cells through a reversible competition effect on histamine receptor sites of these cells. Antazoline hydrochloride can exert an antiallegic effect and prevent the occurrence of physiological reactions from the effect of blocking as well as inhibiting H1 receptor. Antazoline hydrochloride can effectively reduce HBV DNA in the extracellular supernatant in a dose-dependent manner, with EC50 of 2.910 μmol/L in HepAD38 cells. Antazoline hydrochloride also has a significant inhibitory effect on HBV DNA in the extracellular supernatant of Huh7 cells (EC50 = 2.349 μmol/L). Antazoline hydrochloride has anti-arrhythmic effect in acute myocardial infarctions. Antazoline hydrochloride can be studied in research for cardiovascular diseases, and HBV.

分子量

301.81

Formula

C17H20ClN3
CAS 号
中文名称

盐酸安他唑啉 (Standard)
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Antazoline hydrochloride (Standard) 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antazoline hydrochloride (Standard)2508-72-7Phenazoline hydrochloride (Standard)盐酸安他唑啉 (Standard)Reference StandardsHistamine ReceptorHBVHepatitis B virusInhibitorinhibitorinhibit

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