2. Immunology/Inflammation
  3. Transmembrane Glycoprotein
  4. Anti-Mouse CD90.2 Antibody (30H12)

Anti-Mouse CD90.2 Antibody (30H12) 

目录号: HY-P99131 纯度: 95.00%
COA 技术支持

Anti-Mouse CD90.2 Antibody (30H12) 是一种源自大鼠宿主的抗小鼠 CD90.2 IgG2b 抗体抑制剂。Anti-Mouse CD90.2 Antibody (30H12) 可消耗固有淋巴细胞 (ILC) 和 T 细胞。Anti-Mouse CD90.2 Antibody (30H12) 可用于感染、炎症和免疫学研究，如小肠结肠炎耶尔森菌 (Yersinia enterocolitica) 感染和气道炎症。

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Anti-Mouse CD90.2 Antibody (30H12)

Anti-Mouse CD90.2 Antibody (30H12) Chemical Structure

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规格 价格 是否有货 数量
1 mg ￥2000
In-stock
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100 mg   询价  

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Anti-Mouse CD90.2 Antibody (30H12) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Mouse CD90.2 Antibody (30H12) is an anti-mouse CD90.2 IgG2b antibody inhibitor derived from host Rat. Anti-Mouse CD90.2 Antibody (30H12) can deplete innate lymphoid cells (ILC) and T cells. Anti-Mouse CD90.2 Antibody (30H12) can be used for the researches of infection, inflammation and immunology, such as Yersinia enterocolitica infection and airway inflammation[1][2].

同型

Rat IgG2b kappa
推荐同型对照抗体
反应种属

Human/Mouse
体内研究
(In Vivo)

Anti-Mouse CD90.2 Antibody (30H12) (100 μg/mouse，腹腔注射，在第 -4, -1, 2, 5 天给药) 可清除先天性淋巴细胞 (ILC)，并降低感染小肠结肠炎耶尔森菌的 Rag1−/− 小鼠的存活率[1]。
Anti-Mouse CD90.2 Antibody (30H12) (500 μg/mouse，腹腔注射，每隔一天一次，共 4 次) 可清除 2 型先天性淋巴细胞 (ILC2)，并减轻臭氧诱导小鼠的气道炎症和高反应性[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rag1−/− mice with Yersinia enterocolitica infection[1]
Dosage: 500 μg/mouse
Administration: Intraperitoneally injection, at days -4, -1, 2, 5
Result: Depleted ILC and most NK cells in the small intestinal lamina propria.
Had a decreased survival rate and rapid weight loss.
Increased bacterial burden in the ileum, spleen and liver.
Animal Model: Ozone-induced mice[2]
Dosage: 100 μg/mouse
Administration: Intraperitoneally injection, every other day for 4 times
Result: Depleted ILC2 and T cells.
Reduced total cell count and neutrophil and abolished eosinophils in the BAL fluid.
Abolished IL-5 release in the BAL.
应用

ELISA, FACS, Functional assay, Research in vivo
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
分子量

150 kDa

性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Anti-Mouse CD90.2 Antibody (30H12) 相关分类

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-Mouse CD90.2 Antibody (30H12)Transmembrane GlycoproteinCD90.2Lymphoid cellsT cellsYersinia enterocoliticaIL-5Inhibitorinhibitorinhibit

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