2. Cell Cycle/DNA Damage Cytoskeleton
  3. PAK
  4. AZ13711265

AZ13711265 是一种具有高选择性和口服活性的 PAK1 抑制剂。AZ13711265 对 PAK1 和 pPAK1 的 IC50 分别为 0.58 nM 和 0.11 µM。AZ13711265 具有低亲脂性、低清除率，可作为 PAK1 体内探针化合物。AZ13711265 可用于癌症的研究。

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AZ13711265

AZ13711265 Chemical Structure

CAS No. : 2016806-55-4

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AZ13711265 相关抗体

Top Publications Citing Use of Products

查看 PAK 亚型特异性产品:

查看所有亚型
PAK1 PAK2 PAK3 PAK4 PAK5 PAK6

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AZ13711265 is an orally active PAK1 inhibitor with high selectivity. AZ13711265 has IC50 values of 0.58 nM and 0.11 µM for PAK1 and pPAK1, respectively. AZ13711265 has low lipophilicity and low clearance, and can be used as an in vivo probe compound for PAK1. AZ13711265 can be used in the study of cancer[1].

IC50 & Target[1]

PAK1

0.58 nM (IC50)

pPAK1

0.11 μM (IC50)

分子量

554.68

Formula

C28H35FN6O3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AZ13711265 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AZ137112652016806-55-4AZ 13711265AZ-13711265PAKp21 activated kinasesMCF10A cell lineOVCAR3 cell lineMousecancerInhibitorinhibitorinhibit

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产品名称：
AZ13711265
目录号：
HY-119216
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