1. Antibody-drug Conjugate/ADC Related Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  2. Antibody-Drug Conjugates (ADCs) EGFR
  3. BL-B01D1

BL-B01D1 是一种双特异性 ADC,通过双特异性抗体 Izalontamab (HY-P99676) 靶向 EGFR 和 HER3,并通过其 ADC 毒素 ED04 (HY-153891) 抑制 DNA 复制和 DNA 合成,对各种癌细胞表现出细胞毒性。

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BL-B01D1 Chemical Structure

BL-B01D1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
1 mg ¥13050
In-stock
5 mg   询价  
10 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BL-B01D1 is a bispecific ADC, which targets EGFR and HER3 through bispecific antibody Izalontamab (HY-P99676), and exhibits cytotoxicity against various cancer cells via inhibition of DNA replication and DNA synthesis by its ADC toxin ED04 (HY-153891)[1].

分子量

205830.00

性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.

储存方式

-80°C, protect from light

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
BL-B01D1
目录号:
HY-164702
需求量: