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  3. C-Type Natriuretic Peptide (1-53), human

C-Type Natriuretic Peptide (1-53), human 

目录号: HY-P1815
产品使用指南

C-Type Natriuretic Peptide (1-53), human 是 C-型钠尿肽的 1-53 片段。C-Type Natriuretic Peptide 是利尿钠肽家族肽,其参与维持电解质-液体平衡和血管张力。

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Custom Peptide Synthesis

C-Type Natriuretic Peptide (1-53), human Chemical Structure

C-Type Natriuretic Peptide (1-53), human Chemical Structure

CAS No. : 141294-77-1

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Description

C-Type Natriuretic Peptide (1-53), human is the 1-53 fragment of C-Type Natriuretic Peptide. C-Type Natriuretic Peptide is natriuretic peptide family peptide that is involved in the maintenance of electrolyte-fluid balance and vascular tone[1].

Molecular Weight

5801.77

Formula

C₂₅₁H₄₁₇N₈₁O₇₁S₃

CAS No.

141294-77-1

Sequence

{Asp}{Leu}{Arg}{Val}{Asp}{Thr}{Lys}{Ser}{Arg}{Ala}{Ala}{Trp}{Ala}{Arg}{Leu}{Leu}{Gln}{Glu}{His}{Pro}{{Asn}{Ala}{Arg}{Lys}{Tyr}{Lys}{Gly}{Ala}{Asn}{Lys}{Lys}{Gly}{Leu}{Ser}{Lys}{Gly}{Cys}{Phe}{Gly}{Leu}{Lys}{Leu}{Asp}{Arg}{Ile}{Gly}{Ser}{Met}{Ser}{Gly}{Leu}{Gly}{Cys}

Sequence Shortening

DLRVDTKSRAAWARLLQEHPNARKYKGANKKGLSKGCFGLKLDRIGSMSGLGC

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

H2O

Peptide Solubility and Storage Guidelines:

1.  Calculate the length of the peptide.

2.  Calculate the overall charge of the entire peptide according to the following table:

  Contents Assign value
Acidic amino acid Asp (D), Glu (E), and the C-terminal -COOH. -1
Basic amino acid Arg (R), Lys (K), His (H), and the N-terminal -NH2 +1
Neutral amino acid Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q) 0

3.  Recommended solution:

Overall charge of peptide Details
Negative (<0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, add NH4OH (<50 μL).
3.  If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0) 1.  Try to dissolve the peptide in water first.
2.  If water fails, try dissolving the peptide in a 10%-30% acetic acid solution.
3.  If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0) 1.  Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first.
2.  For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.
References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
C-Type Natriuretic Peptide (1-53), human
目录号:
HY-P1815
需求量:

C-Type Natriuretic Peptide (1-53), human

Cat. No.: HY-P1815