1. Others Anti-infection
  2. Drug Derivative Antibiotic Bacterial
  3. CB-182804

CB-182804 是 Polymyxin B (HY-149179) 的类似物,是一种多肽类抗生素。CB-182804 对所有革兰氏阴性致病菌均有抑制活性,包括大肠杆菌 (Escherichia coli)、肺炎克雷伯菌 (Klebsiella pneumoniae)、鲍曼不动杆菌 (Acinetobacter baumannii) 和铜绿假单胞菌 (Pseudomonas aeruginosa),其 MIC50 值均为 2 μg/mL。CB-182804 主要用于耐多药 (MDR) 革兰氏阴性菌引起的难治性感染研究。

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CB-182804

CB-182804 Chemical Structure

CAS No. : 1231767-35-3

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

CB-182804, Polymyxin B (HY-149179) analogue, is a polypeptide antibiotic. CB-182804 has inhibitory activity against all Gram-negative pathogenic bacteria, including Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, and Pseudomonas aeruginosa with MIC50 values of 2 μg/mL. CB-182804 is mainly used for the research on refractory infections caused by multidrug-resistant (MDR) Gram-negative bacteria[1].

分子量

1216.82

Formula

C54H86ClN17O13

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CB-182804
目录号:
HY-107120
需求量: