2. Anti-infection
  3. Penicillin-binding protein (PBP) Antibiotic Bacterial
  4. Cephalexin hydrochloride monohydrate

Cephalexin hydrochloride monohydrate  (Synonyms: 头孢氨苄单盐酸盐; Cefalexin hydrochloride monohydrate; Cephacillin hydrochloride monohydrate)

目录号: HY-B0200C
产品使用指南

摩尔计算器

Cephalexin (Cefalexin) hydrochloride monohydrate 是一种口服有效的新型半合成头孢菌素抗生素 (antibiotic)，具有广泛的抗菌谱。Cephalexin (Cefalexin) hydrochloride monohydrate 对多种革兰氏阳性和革兰氏阴性细菌具有抗菌活性。Cephalexin (Cefalexin) hydrochloride monohydrate 靶向青霉素结合蛋白 (PBPs)，以抑制细菌细胞壁组装。Cephalexin (Cefalexin) hydrochloride monohydrate 用于肺炎、链球菌性咽喉炎、细菌性心内膜炎等的研究。

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Cephalexin hydrochloride monohydrate Chemical Structure

Cephalexin hydrochloride monohydrate Chemical Structure

CAS No. : 105879-42-3

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Cephalexin hydrochloride monohydrate 的其他形式现货产品:

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Other Forms of Cephalexin hydrochloride monohydrate:

Cephalexin hydrochloride monohydrate 相关抗体

Top Publications Citing Use of Products

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cephalexin (Cefalexin) hydrochloride monohydrate is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin (Cefalexin) hydrochloride monohydrate has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) hydrochloride monohydrate targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin (Cefalexin) hydrochloride monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al[1][2].

IC50 & Target

β-lactam

 

体外研究
(In Vitro)

Cephalexin (Cefalexin) hydrochloride monohydrate (10 μg/mL) disrupts polymer peptidoglycan (PG) biogenesis by inactivating enzymes called penicillin-binding proteins (PBPs)[1].
Cephalexin (Cefalexin) hydrochloride monohydrate inhibits a broad spectrum of grampositive and gram-negative organisms with MIC values of 2, 2, 2, 2, 4, 4.4 and 5.7 μg/mL for Bacillus anthracis, Edwardsiella taFda, Vibrio cholera, Pasteurella multocida, Edwardsiella tarda, Alcaligenes sp and Proteus rettgeri, respectively[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cephalexin hydrochloride monohydrate 相关抗体:
体内研究
(In Vivo)

Cephalexin (Cefalexin) hydrochloride monohydrate (0-50 mg/kg; p.o.; for 3.5 hours) has antibacterial activity in male Swiss-Webster mice with infected bacterial[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Swiss-Webster mice with infected bacterial[2]
Dosage: 0-50 mg/kg
Administration: Oral administration; for 3.5 hours
Result: Had antibacterial activity against Streptococcus pyogenes, Streptococcus pneumoniae, Staphylococcus aureus and several gram-negative species mice.
Clinical Trial
分子量

401.87

Formula

C16H20ClN3O5S
CAS 号
中文名称

头孢氨苄单盐酸盐
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cephalexin hydrochloride monohydrate 相关分类

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  • 稀释计算器

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cephalexin hydrochloride105879-42-3Cefalexin hydrochlorideCephacillin hydrochloride头孢氨苄单盐酸盐Penicillin-binding protein (PBP)AntibioticBacterialgram-positive bacteriagram-negative bacteriapenicillin-binding proteinscell wall assemblyInhibitorinhibitorinhibit

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