2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. Cys-GE11

Cys-GE11 是一种半胱氨酸修饰的短肽。Cys-GE11 通过半胱氨酸的 N 端可与 PEG-P(TMC-DTC) 连接形成靶向聚合物。Cys-GE11 可以靶向 EGFR 高表达的细胞 (如 SMMC-7721 细胞)。Cys-GE11 可以显著增强肿瘤部位的药物富集，并表现出低毒性。

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Custom Peptide Synthesis

Cys-GE11

Cys-GE11 Chemical Structure

CAS No. : 1421680-54-7

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Cys-GE11 相关抗体

Top Publications Citing Use of Products

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EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cys-GE11 is a short peptide modified with cysteine. Cys-GE11 can be linked to PEG-P (TMC-DTC) through the N-terminus of cysteine to form a targeted polymer. Cys-GE11 can target cells with high EGFR expression (such as SMMC-7721 cells). Cys-GE11 can significantly enhance drug enrichment at the tumor site and exhibit low toxicity[1].

分子量

1643.82

Formula

C78H102N18O20S
CAS 号
Sequence

Cys-Tyr-His-Trp-Tyr-Gly-Tyr-Thr-Pro-Gln-Asn-Val-Ile
Sequence Shortening

CYHWYGYTPQNVI
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cys-GE11 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cys-GE111421680-54-7EGFREpidermal growth factor receptorErbB-1HER1peptidecysteineSMMC-7721Inhibitorinhibitorinhibit

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