D-myo-Inositol-1,2,6-triphosphate sodium  (Synonyms: Ins(1,2,6)-P3; 1,2,6-IP3)

D-myo-Inositol-1,2,6-triphosphate (sodium) is one of the members in inositol phosphate family of second messengers that play an important role in transmitting cellular signals. D-myo-Inositol-1,2,6-triphosphate (sodium) can open calcium channels and increase intracellular calcium upon binding to its receptor on the endoplasmic reticulum^[1][2][3][4].

486.04

C₆H₁₂Na₃O₁₅P₃

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Majerus P. W. (1992). Inositol phosphate biochemistry. Annual review of biochemistry, 61, 225–250.  [Content Brief]

  [2]. Berridge M. J. (2009). Inositol trisphosphate and calcium signalling mechanisms. Biochimica et biophysica acta, 1793(6), 933–940.  [Content Brief]

  [3]. Yoshida, Y., & Imai, S. (1997). Structure and function of inositol 1,4,5-trisphosphate receptor. Japanese journal of pharmacology, 74(2), 125–137.  [Content Brief]

  [4]. Exton J. H. (1996). Regulation of phosphoinositide phospholipases by hormones, neurotransmitters, and other agonists linked to G proteins. Annual review of pharmacology and toxicology, 36, 481–509.  [Content Brief]