1. MAPK/ERK Pathway
  2. p38 MAPK
  3. Deoxysappanone B

Deoxysappanone B  (Synonyms: 3-Deoxysappanone B)

目录号: HY-N1818
产品使用指南

Deoxysappanone B (3-Deoxysappanone B) 是一种从 Caesalpinia sappan L (Lignum Sappan) 分离得到的异黄酮化合物。Deoxysappanone B 具有抗神经炎症和神经保护作用,可以通过阻断 IκB kinase (IKK)-NF-κB 和 p38/ERK MAPK 途径的信号通路,抑制神经炎症介质的产生。Deoxysappanone B 可用于神经炎和炎症相关的神经损伤的疾病研究。

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Deoxysappanone B Chemical Structure

Deoxysappanone B Chemical Structure

CAS No. : 113122-54-6

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Deoxysappanone B (3-Deoxysappanone B) is a homoisoflavone compound isolated from Caesalpinia sappan L (Lignum Sappan). Deoxysappanone B has anti-neuroinflammatory and neuroprotective effects and inhibits the production of neuroinflammatory mediators by blocking the IκB kinase (IKK)-NF-κB and p38/ERK MAPK pathways. Deoxysappanone B can be used in disease studies of neuritis and inflammation-related neurological damage[1].

分子量

286.28

Formula

C16H14O5

CAS 号
中文名称

3-脱氧苏木酮 B

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Deoxysappanone B 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Deoxysappanone B
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HY-N1818
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