1. GPCR/G Protein
    Apoptosis
  2. Ras
    Apoptosis
  3. Diazepinomicin

Diazepinomicin (Synonyms: ECO-4601; TLN-4601; BU 4664L)

目录号: HY-N6674
产品使用指南

Diazepinomicin (TLN-4601) 是Micromonospora sp 的次生代谢产物,可抑制EGF 诱导的 Ras-ERK MAPK 信号通路,可诱导凋亡。是一种可用于 K-Ras 突变型的抗肿瘤药物。

MCE 的所有产品仅用作科学研究,我们不为任何个人用途提供产品和服务

Diazepinomicin Chemical Structure

Diazepinomicin Chemical Structure

CAS No. : 733035-26-2

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

Size Stock
100 mg Get quote
250 mg Get quote

* Please select Quantity before adding items.

Customer Review

Top Publications Citing Use of Products

View All Ras Isoform Specific Products:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

Description

Diazepinomicin (TLN-4601) is a secondary metabolite produced by Micromonospora sp. Diazepinomicin (TLN-4601) inhibits the EGF-induced Ras-ERK MAPK signaling pathway and induces apoptosis. An anti-tumor agent for K-Ras mutant models[1].

IC50 & Target

Diazepinomicin (TLN-4601) inhibits the EGF-induced Ras-ERK MAPK signaling pathway post Ras prenylation and prior to MEK activation[1].

Clinical Trial
Molecular Weight

462.58

Formula

C₂₈H₃₄N₂O₄

CAS No.

733035-26-2

SMILES

O=C1C2=CC=CC(O)=C2NC3=C(O)C=C(O)C=C3N1C/C=C(C)/CC/C=C(C)/CC/C=C(C)\C

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Diazepinomicin
目录号:
HY-N6674
需求量:

Diazepinomicin

Cat. No.: HY-N6674