2. Protein Tyrosine Kinase/RTK PI3K/Akt/mTOR MAPK/ERK Pathway Stem Cell/Wnt Apoptosis
  3. FGFR Akt ERK mTOR Apoptosis
  4. FGF7p

FGF7p 是一种小分子肽，一种具有潜力的膀胱保护剂。FGF7p 可以激活尿路上皮的 FGFR2 下游信号通路 (pFRS2α、pAKT、pERK)。FGF7p 通过激活 AKT 及其下游抗凋亡 (apoptosis) 靶点 (pBAD、pS6/mTORC1) 减轻环磷酰胺引起的尿路上皮细胞凋亡和组织损伤。FGF7p 具有成本低、稳定性好、纯度高等优势。FGF7p 常用于炎症疾病的研究。

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FGF7p

FGF7p Chemical Structure

CAS No. : 2758194-43-1

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规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

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Customer Review

FGF7p 相关抗体

Top Publications Citing Use of Products

查看 Akt 亚型特异性产品:

查看所有亚型
Akt Akt1 Akt2 Akt3

查看 ERK 亚型特异性产品:

查看所有亚型
ERK ERK1 ERK2 ERK5 ERK8

查看 mTOR 亚型特异性产品:

查看所有亚型
mTOR mTORC1 mTORC2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FGF7p is a small molecule peptide and a potential bladder protector. FGF7p can activate downstream signaling pathways of FGFR2 in the urinary tract epithelium (pFRS2α, pAKT and pERK). FGF7p alleviates cyclophosphamide induced apoptosis and tissue damage in urinary tract epithelial cells by activating AKT and its downstream anti apoptotic targets (pBAD, pS6/mTORC1). FGF7p has the advantages of low cost, good stability, and high purity. FGF7p is commonly used in the study of inflammatory conditions[1].

IC50 & Target[1]

Akt

 

FGFR2

 

ERK

 

mTORC1

 

分子量

2124.33

Formula

C95H138N26O28S
CAS 号
Sequence

Tyr-Ala-Ser-Ala-Lys-Trp-Thr-His-Asn-Gly-Gly-Glu-Met-Phe-Val-Ala-Leu-Asn-Gln
Sequence Shortening

YASAKWTHNGGEMFVALNQ
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

FGF7p 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FGF7p2758194-43-1FGFRAktERKmTORApoptosisFibroblast growth factor receptorPKBProtein kinase BExtracellular signal regulated kinasesMammalian target of RapamycinpeptideFGFR2pFRS2αpAKTpERKpBADpS6/mTORC1Inhibitorinhibitorinhibit

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目录号：
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