2. Immunology/Inflammation
  3. COX
  4. Florifenine

Florifenine 是一种选择性环氧合酶 (COX) 抑制剂，具有抗炎活性。Florifenine 对人全血中的 TXB2 具有抑制作用，IC50 为 32.5 nM。Florifenine 在耳廓水肿中表现出抗炎作用。Florifenine 抑制中性粒细胞迁移并降低炎症耳廓中的 PGE2 水平。Florifenine 抑制 Zymosan (HY-159069) 诱导的气囊炎症中的白细胞迁移和 PGE2 水平。Florifenine 可用于抗炎研究。

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Florifenine

Florifenine Chemical Structure

CAS No. : 83863-79-0

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Florifenine 相关抗体

Top Publications Citing Use of Products

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COX COX-1 COX-2 COX-3

  • 生物活性

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  • 参考文献

生物活性

Florifenine is a selective cyclooxygenase (COX) inhibitor with anti-inflammatory activity. Florifenine inhibits TXB2 in human whole blood with an IC50 of 32.5 nM. Florifenine exhibits anti-inflammatory effects in ear oedema. Florifenine inhibits neutrophil migration and reduces PGE2 levles in the inflamed ears. Florifenine inhibits leukocyte migration and PGE2 levels in the air pouch inflammation induced by Zymosan (HY-159069). Florifenine can be used for anti-inflammatory research[1].

分子量

429.43

Formula

C23H22F3N3O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Florifenine 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Florifenine83863-79-0COXCyclooxygenasecyclooxygenaseanti-inflammatoryArachidonic acid12-O-tetradecanoylphorbol 13-acetateear oedemaneutrophilPGE2leukocyteZymosanInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-105424
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