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  2. ZNF717 - zinc finger protein 717 Gene

ZNF717 - zinc finger protein 717 Gene

中文名称:锌指蛋白 717

种属: Homo sapiens

同用名: OB1; X17; ZNF838

基因 ID: 100131827 | 基因类型: protein coding

关于 ZNF717

Cytogenetic location: 3p12.3 Genomic coordinates (GRCh38): 3:75,694,701-75,785,549 (from NCBI)

This gene has 7 transcripts (splice variants), 20 orthologues and 174 paralogues. Ubiquitous expression in testis (RPKM 1.7), thyroid (RPKM 1.6) and 25 other tissues.

功能概要

该基因编码 Kruppel 相关盒 (KRAB) 锌指蛋白,属于哺乳动物中一大类转录调节因子。这些蛋白质结合核酸并在各种细胞功能中发挥重要作用,包括细胞增殖、分化和凋亡,以及调节病毒复制和转录。在 1 号染色体上鉴定出该基因的假基因。[RefSeq 提供,2016 年 5 月]

This gene encodes a Kruppel-associated box (KRAB) zinc-finger protein, which belongs to a large group of transcriptional regulators in mammals. These proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation and Apoptosis, and in regulating viral replication and transcription. A pseudogene of this gene was identified on chromosome 1. [provided by RefSeq, May 2016]

ZNF717 基因产物(7)

mRNA Protein Name
NM_001128223.3 NP_001121695.1 zinc finger protein 717 isoform a
NM_001290208.3 NP_001277137.1 zinc finger protein 717 isoform a
NM_001290209.3 NP_001277138.1 zinc finger protein 717 isoform b
NM_001290210.2 NP_001277139.1 zinc finger protein 717 isoform c
NM_001324026.2 NP_001310955.1 zinc finger protein 717 isoform c
NM_001324027.1 NP_001310956.1 zinc finger protein 717 isoform d
NM_001324028.1 NP_001310957.1 zinc finger protein 717 isoform e

ZNF717 蛋白结构

KRAB

KRAB: KRAB box (15 - 55)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (263 - 283)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (320 - 342)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (347 - 370)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (375 - 398)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (403 - 427)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (431 - 453)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (458 - 482)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (487 - 510)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (515 - 539)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (543 - 566)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (571 - 594)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (601 - 622)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (626 - 650)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (738 - 760)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (765 - 789)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (794 - 817)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (824 - 845)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (850 - 872)

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  • 907 a.a.
蛋白主名 其他名称

zinc finger protein 717

krueppel-like factor X17

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ZNF717 RGD RGD:1306633
Mus musculus ZNF717 MGD MGI:99183