2. Gene
  3. NME6 - NME/NM23 nucleoside diphosphate kinase 6 Gene

NME6 - NME/NM23 nucleoside diphosphate kinase 6 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：NME/NM23 核苷二磷酸激酶 6

种属: Homo sapiens

同用名: NDK 6; NM23-H6; IPIA-ALPHA

基因 ID: 10201 | 基因类型: protein coding

关于 NME6

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:48,288,402-48,301,367 (from NCBI)

This gene has 22 transcripts (splice variants), 182 orthologues and 8 paralogues. Ubiquitous expression in thyroid (RPKM 3.8), ovary (RPKM 2.8) and 25 other tissues.

功能概要

核苷二磷酸 (NDP) 激酶 (EC 2.7.4.6) ，例如 NME6，是一种普遍存在的酶，可通过磷酸组氨酸中间体在核苷和二氧核苷三磷酸和二磷酸之间催化 γ-磷酸转移 (Mehus 等人，1999 [PubMed] 10453732]) .[OMIM 提供，2010 年 7 月]

Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6), such as NME6, are ubiquitous Enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates (Mehus et al., 1999 [PubMed 10453732]).[supplied by OMIM, Jul 2010]

NME6 基因产物(9)

mRNA Protein Name
NM_001308426.2 NP_001295355.1 nucleoside diphosphate kinase 6 isoform 2
NM_001308427.2 NP_001295356.1 nucleoside diphosphate kinase 6 isoform 2
NM_001308428.2 NP_001295357.1 nucleoside diphosphate kinase 6 isoform 2
NM_001308430.2 NP_001295359.1 nucleoside diphosphate kinase 6 isoform 3
NM_001308431.2 NP_001295360.1 nucleoside diphosphate kinase 6 isoform 4
NM_001308433.2 NP_001295362.1 nucleoside diphosphate kinase 6 isoform 4
NM_001308434.2 NP_001295363.1 nucleoside diphosphate kinase 6 isoform 5
NM_001308435.2 NP_001295364.1 nucleoside diphosphate kinase 6 isoform 6
NM_005793.5 NP_005784.1 nucleoside diphosphate kinase 6 isoform 1

NME6 蛋白结构

NDK

NDK: Nucleoside diphosphate kinase (13 - 147)

  • 0
  • 100
  • 186 a.a.
蛋白主名 其他名称

nucleoside diphosphate kinase 6

NDP kinase 6

关联疾病

疾病名称 别名
Lymph Node Carcinoma

Lymph Node Cancer

Lymph Node Neoplasm

Neoplasm Of Lymph Node
Primary Ciliary Dyskinesia

Immotile Cilia Syndrome

Kartagener Syndrome

Dextrocardia Bronchiectasis And Sinusitis

Pcd

Ciliary Motility Disorders

Ciliary Motility Disorder

Immotile Ciliary Syndrome

Ciliary Dyskinesia Primary

Ics

Polynesian Bronchiectasis

Dextrocardia-Bronchiectasis-Sinusitis Syndrome

Immotile Cilia Syndrome, Kartagener Type

Primary Ciliary Dyskinesia And Situs Inversus

Primary Ciliary Dyskinesia, Kartagener Type

Siewert Syndrome

Dyskinesia, Ciliary, Primary
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P10428 E6AP-mimicking peptide Inhibitor / 否
HY-RS09377 NME6 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus NME6 VGNC VGNC:32128
Felis catus NME6 VGNC VGNC:63836
Macaca mulatta NME6 VGNC VGNC:75222
Canis familiaris NME6 VGNC VGNC:43857
Rattus norvegicus NME6 RGD RGD:61896
Mus musculus NME6 MGD MGI:1861676
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