1. Gene
  2. N4BP2L2 - NEDD4 binding protein 2 like 2 Gene

N4BP2L2 - NEDD4 binding protein 2 like 2 Gene

中文名称:NEDD4 结合蛋白 2 like 2

种属: Homo sapiens

同用名: CG005; CG016; PFAAP5; 92M18.3

基因 ID: 10443 | 基因类型: protein coding

关于 N4BP2L2

Cytogenetic location: 13q13.1 Genomic coordinates (GRCh38): 13:32,432,485-32,538,868 (from NCBI)

This gene has 45 transcripts (splice variants), 175 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 5.4), ovary (RPKM 5.3) and 25 other tissues.

功能概要

启用酶结合活性。参与造血干细胞分化的负调控和造血干细胞增殖的正调控。位于核内。转录抑制复合物的一部分。 [由基因组资源联盟提供,2022 年 4 月]

Enables Enzyme binding activity. Involved in negative regulation of hematopoietic stem cell differentiation and positive regulation of hematopoietic stem cell proliferation. Located in nucleus. Part of transcription repressor complex. [provided by Alliance of Genome Resources, Apr 2022]

N4BP2L2 基因产物(39)

mRNA Protein Name
NM_001278432.2 NP_001265361.1 NEDD4-binding protein 2-like 2 isoform 3
NM_001320836.3 NP_001307765.1 NEDD4-binding protein 2-like 2 isoform 4
NM_001387001.1 NP_001373930.1 NEDD4-binding protein 2-like 2 isoform 4
NM_001387002.1 NP_001373931.1 NEDD4-binding protein 2-like 2 isoform 4
NM_001387004.1 NP_001373933.1 NEDD4-binding protein 2-like 2 isoform 5
NM_001387005.1 NP_001373934.1 NEDD4-binding protein 2-like 2 isoform 6
NM_001387006.1 NP_001373935.1 NEDD4-binding protein 2-like 2 isoform 6
NM_001387008.1 NP_001373937.1 NEDD4-binding protein 2-like 2 isoform 7
NM_001387009.1 NP_001373938.1 NEDD4-binding protein 2-like 2 isoform 7
NM_001387015.1 NP_001373944.1 NEDD4-binding protein 2-like 2 isoform 3
NM_001387016.1 NP_001373945.1 NEDD4-binding protein 2-like 2 isoform 9
NM_001387017.1 NP_001373946.1 NEDD4-binding protein 2-like 2 isoform 5
NM_001387018.1 NP_001373947.1 NEDD4-binding protein 2-like 2 isoform 3
NM_001387019.1 NP_001373948.1 NEDD4-binding protein 2-like 2 isoform 3
NM_001387020.1 NP_001373949.1 NEDD4-binding protein 2-like 2 isoform 8
NM_001387059.1 NP_001373988.1 NEDD4-binding protein 2-like 2 isoform 19
NM_001387060.1 NP_001373989.1 NEDD4-binding protein 2-like 2 isoform 12
NM_001387079.1 NP_001374008.1 NEDD4-binding protein 2-like 2 isoform 12
NM_001387080.1 NP_001374009.1 NEDD4-binding protein 2-like 2 isoform 2
NM_001387081.1 NP_001374010.1 NEDD4-binding protein 2-like 2 isoform 15
NM_001387082.1 NP_001374011.1 NEDD4-binding protein 2-like 2 isoform 2
NM_001387083.1 NP_001374012.1 NEDD4-binding protein 2-like 2 isoform 16
NM_001387099.1 NP_001374028.1 NEDD4-binding protein 2-like 2 isoform 20
NM_001387100.1 NP_001374029.1 NEDD4-binding protein 2-like 2 isoform 17
NM_001387101.1 NP_001374030.1 NEDD4-binding protein 2-like 2 isoform 2
NM_001387102.1 NP_001374031.1 NEDD4-binding protein 2-like 2 isoform 2
NM_001387103.1 NP_001374032.1 NEDD4-binding protein 2-like 2 isoform 10
NM_001387104.1 NP_001374033.1 NEDD4-binding protein 2-like 2 isoform 11
NM_001387105.1 NP_001374034.1 NEDD4-binding protein 2-like 2 isoform 12
NM_001387106.1 NP_001374035.1 NEDD4-binding protein 2-like 2 isoform 12
NM_001387107.1 NP_001374036.1 NEDD4-binding protein 2-like 2 isoform 13
NM_001387108.1 NP_001374037.1 NEDD4-binding protein 2-like 2 isoform 13
NM_001387165.1 NP_001374094.1 NEDD4-binding protein 2-like 2 isoform 18
NM_001387223.1 NP_001374152.1 NEDD4-binding protein 2-like 2 isoform 16
NM_001387224.1 NP_001374153.1 NEDD4-binding protein 2-like 2 isoform 15
NM_001387225.1 NP_001374154.1 NEDD4-binding protein 2-like 2 isoform 14
NM_001395224.1 NP_001382153.1 NEDD4-binding protein 2-like 2 isoform 21
NM_014887.3 NP_055702.1 NEDD4-binding protein 2-like 2 isoform 2
NM_033111.5 NP_149102.3 NEDD4-binding protein 2-like 2 isoform 1

N4BP2L2 蛋白结构

AAA_33

AAA_33: AAA domain (404 - 536)

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  • 583 a.a.
蛋白主名 其他名称

NEDD4-binding protein 2-like 2

phosphonoformate immuno-associated protein 5

直系同源

种属 基因名 来源 基因 ID
Mus musculus N4BP2L2 MGD MGI:2687207
Macaca mulatta N4BP2L2 VGNC VGNC:75031
Canis familiaris N4BP2L2 VGNC VGNC:59086
Rattus norvegicus N4BP2L2 RGD RGD:1359603
Bos taurus N4BP2L2 VGNC VGNC:53827