ARPC1A - actin related protein 2/3 complex subunit 1A Gene

中文名称：肌动蛋白相关蛋白 2/3 复合亚基 1A

种属: Homo sapiens

同用名: Arc40; SOP2L; HEL-68; SOP2Hs; HEL-S-307

关于 ARPC1A

功能概要

该基因编码人类 Arp2/3 蛋白复合物的七个亚基之一。该亚基是 SOP2 蛋白质家族的成员，与 ARPC1B 基因编码的蛋白质最相似。这两种蛋白质之间的相似性表明它们都可能作为人类 Arp2/3 复合体的 p41 亚基发挥作用，该复合体与细胞中肌动蛋白聚合的控制有关。 p41 亚基可能参与组装和维持 Arp2/3 复合体的结构。 p41 亚基的多个版本可以使复合体的功能适应不同的细胞类型或发育阶段。已发现该基因编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2010 年 7 月]

This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]