2. Gene
  3. ARPP21 - cAMP regulated phosphoprotein 21 Gene

ARPP21 - cAMP regulated phosphoprotein 21 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：cAMP 调节磷蛋白 21

种属: Homo sapiens

同用名: RCS; TARPP; R3HDM3; ARPP-21

基因 ID: 10777 | 基因类型: protein coding

关于 ARPP21

Cytogenetic location: 3p22.3 Genomic coordinates (GRCh38): 3:35,638,853-35,794,486 (from NCBI)

This gene has 36 transcripts (splice variants), 134 orthologues and 2 paralogues. Biased expression in brain (RPKM 4.3) and esophagus (RPKM 0.1).

功能概要

该基因编码 cAMP 调节的磷蛋白。编码的蛋白质在尾状核和小脑皮质中富集。小鼠中的一种类似蛋白质可能参与调节基底神经节中多巴胺的作用。交替剪接导致多个转录本变体。[RefSeq 提供，2012 年 6 月]

This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

ARPP21 基因产物(49)

mRNA Protein Name
NM_001025068.1 NP_001020239.1 cAMP-regulated phosphoprotein 21 isoform 2
NM_001025069.1 NP_001020240.1 cAMP-regulated phosphoprotein 21 isoform 2
NM_001267616.2 NP_001254545.1 cAMP-regulated phosphoprotein 21 isoform 2
NM_001267617.2 NP_001254546.1 cAMP-regulated phosphoprotein 21 isoform 3
NM_001267618.2 NP_001254547.1 cAMP-regulated phosphoprotein 21 isoform 2
NM_001267619.2 NP_001254548.1 cAMP-regulated phosphoprotein 21 isoform 4
NM_001385484.1 NP_001372413.1 cAMP-regulated phosphoprotein 21 isoform 4
NM_001385485.1 NP_001372414.1 cAMP-regulated phosphoprotein 21 isoform 4
NM_001385486.1 NP_001372415.1 cAMP-regulated phosphoprotein 21 isoform 4
NM_001385487.1 NP_001372416.1 cAMP-regulated phosphoprotein 21 isoform 4
NM_001385488.1 NP_001372417.1 cAMP-regulated phosphoprotein 21 isoform 3
NM_001385489.1 NP_001372418.1 cAMP-regulated phosphoprotein 21 isoform 3
NM_001385490.1 NP_001372419.1 cAMP-regulated phosphoprotein 21 isoform 6
NM_001385491.1 NP_001372420.1 cAMP-regulated phosphoprotein 21 isoform 14
NM_001385492.1 NP_001372421.1 cAMP-regulated phosphoprotein 21 isoform 3
NM_001385495.1 NP_001372424.1 cAMP-regulated phosphoprotein 21 isoform 7
NM_001385496.1 NP_001372425.1 cAMP-regulated phosphoprotein 21 isoform 13
NM_001385497.1 NP_001372426.1 cAMP-regulated phosphoprotein 21 isoform 3
NM_001385517.1 NP_001372446.1 cAMP-regulated phosphoprotein 21 isoform 15
NM_001385536.1 NP_001372465.1 cAMP-regulated phosphoprotein 21 isoform 9
NM_001385556.1 NP_001372485.1 cAMP-regulated phosphoprotein 21 isoform 12
NM_001385558.1 NP_001372487.1 cAMP-regulated phosphoprotein 21 isoform 8
NM_001385562.1 NP_001372491.1 cAMP-regulated phosphoprotein 21 isoform 6
NM_001385563.1 NP_001372492.1 cAMP-regulated phosphoprotein 21 isoform 10
NM_001385564.1 NP_001372493.1 cAMP-regulated phosphoprotein 21 isoform 4
NM_001385565.1 NP_001372494.1 cAMP-regulated phosphoprotein 21 isoform 3
NM_001385566.1 NP_001372495.1 cAMP-regulated phosphoprotein 21 isoform 11
NM_001385567.1 NP_001372496.1 cAMP-regulated phosphoprotein 21 isoform 8
NM_001385573.1 NP_001372502.1 cAMP-regulated phosphoprotein 21 isoform 10
NM_001385574.1 NP_001372503.1 cAMP-regulated phosphoprotein 21 isoform 3
NM_001385576.1 NP_001372505.1 cAMP-regulated phosphoprotein 21 isoform 3
NM_001385577.1 NP_001372506.1 cAMP-regulated phosphoprotein 21 isoform 3
NM_001385578.1 NP_001372507.1 cAMP-regulated phosphoprotein 21 isoform 3
NM_001385580.1 NP_001372509.1 cAMP-regulated phosphoprotein 21 isoform 3
NM_001385581.1 NP_001372510.1 cAMP-regulated phosphoprotein 21 isoform 3
NM_001385582.1 NP_001372511.1 cAMP-regulated phosphoprotein 21 isoform 10
NM_001385584.1 NP_001372513.1 cAMP-regulated phosphoprotein 21 isoform 10
NM_001385585.1 NP_001372514.1 cAMP-regulated phosphoprotein 21 isoform 9
NM_001385587.1 NP_001372516.1 cAMP-regulated phosphoprotein 21 isoform 4
NM_001385588.2 NP_001372517.1 cAMP-regulated phosphoprotein 21 isoform 4
NM_001385589.1 NP_001372518.1 cAMP-regulated phosphoprotein 21 isoform 8
NM_001385590.1 NP_001372519.1 cAMP-regulated phosphoprotein 21 isoform 8
NM_001385591.1 NP_001372520.1 cAMP-regulated phosphoprotein 21 isoform 7
NM_001385592.1 NP_001372521.1 cAMP-regulated phosphoprotein 21 isoform 6
NM_001385593.1 NP_001372522.1 cAMP-regulated phosphoprotein 21 isoform 16
NM_001385594.1 NP_001372523.1 cAMP-regulated phosphoprotein 21 isoform 6
NM_001385595.1 NP_001372524.1 cAMP-regulated phosphoprotein 21 isoform 5
NM_016300.5 NP_057384.2 cAMP-regulated phosphoprotein 21 isoform 1
NM_198399.2 NP_938409.1 cAMP-regulated phosphoprotein 21 isoform 2

ARPP21 蛋白结构

R3H

R3H: R3H domain (164 - 224)

SUZ

SUZ: SUZ domain (245 - 299)

  • 0
  • 200
  • 400
  • 600
  • 812 a.a.
蛋白主名 其他名称

cAMP-regulated phosphoprotein 21

R3H domain containing 3

关联疾病

疾病名称 别名
Alzheimer Disease 13

AD13

Alzheimer Disease-13

Alzheimer'S Disease 13

Alzheimer'S Disease 13, Late Onset
Bubonic Plague

Black Death

Plague, Bubonic

Plague, Septicemic

Pestis Bubonica
Mesenteric Lymphadenitis

Mesenteric Adenitis
Septicemic Plague

Plague, Septicemic
Intellectual Developmental Disorder, X-Linked 109

Fraxe Syndrome

Fragile Xe Syndrome

Mental Retardation, X-Linked, Fraxe Type

XLID109

Mrx109

Mental Retardation, X-Linked, Associated With Fragile Site Fraxe

Fraxe Mental Retardation Syndrome

X-Linked Intellectual Developmental Disorder 109

Fraxe Intellectual Disability

Fraxe

Mental Retardation, X-Linked 109

Fragile Site On Chromosome Xq28

Fragile Site, Folic Acid Type

X-Linked Intellectual Disability Associated With Fragile Site Fraxe

Fraxe Intellectual Deficit

Intellectual Disability Associated With Fragile Site Fraxe
Rapp-Hodgkin Syndrome

RHS

Anhidrotic Ectodermal Dysplasia With Cleft Lip/Palate

Ectodermal Dysplasia, Rapp-Hodgkin Type

Rapp-Hodgkin Ectodermal Dysplasia Syndrome

Ectodermal Dysplasia, Anhidrotic, With Cleft Lip/Palate

Ectodermal Dysplasia Syndrome, Rapp-Hodgkin Type

Edrh

Rapp-Hodgkin Ectodermal Dysplasia

Orofacial Cleft 8
Alcohol-Related Neurodevelopmental Disorder

Static Encephalopathy

Arnd

Encephalopathy, Static

Alcohol Related Neurodevelopmental Disorder
Plague

Yersiniosis

Yersinia Infections

Infection By Yersinia Pestis

Pasteurella Pestis Infection

Pestilential Fever

Yersinia Pestis Infection
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01026 ARPP21 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ARPP21 RGD RGD:1593239
Mus musculus ARPP21 MGD MGI:107562
Bos taurus ARPP21 VGNC VGNC:58588
Canis familiaris ARPP21 VGNC VGNC:38134
Felis catus ARPP21 VGNC VGNC:59942
Macaca mulatta ARPP21 VGNC VGNC:69845
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