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  3. Grm2 - glutamate receptor, metabotropic 2 Gene

Grm2 - glutamate receptor, metabotropic 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：谷氨酸受体，代谢型 2

种属: Mus musculus

同用名: Gprc1b; mGluR2; mGluR7; 4930441L02Rik

基因 ID: 108068 | 基因类型: protein coding

关于 Grm2

Chromosome 9: 106,520,294-106,533,281 reverse strand.GRCm39:CM001002.3

This gene has 4 transcripts (splice variants), 280 orthologues, 7 paralogues and is associated with 10 phenotypes. Biased expression in frontal lobe adult (RPKM 23.), cortex adult (RPKM 16.8) and 6 other tissues.

功能概要

该基因编码的蛋白可启动钙通道调节剂活性和第 II 组代谢型谷氨酸受体活性。作用于化学突触传递的上游或内部；基因表达;和谷氨酸稳态。位于神经元投射。在大脑中表达。与人类 GRM2（谷氨酸代谢受体 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables Calcium Channel regulator activity and group II metabotropic glutamate receptor activity. Acts upstream of or within chemical synaptic transmission; gene expression; and glutamate homeostasis. Located in neuron projection. Is expressed in brain. Orthologous to human GRM2 (glutamate metabotropic receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Grm2 基因产物(1)

mRNA Protein Name
NM_001160353.1 NP_001153825.1 metabotropic glutamate receptor 2 precursor

Grm2 蛋白结构

PBP1_mGluR_groupII

PBP1_mGluR_groupII: cd06375 (25 - 479)

NCD3G

NCD3G: pfam07562 (495 - 545)

7tmC_mGluR2

7tmC_mGluR2: cd15447 (565 - 818)

7tmC_mGluR2

7tmC_mGluR2: cd15447 (565 - 590)

7tmC_mGluR2

7tmC_mGluR2: cd15447 (602 - 623)

7tmC_mGluR2

7tmC_mGluR2: cd15447 (632 - 656)

7tmC_mGluR2

7tmC_mGluR2: cd15447 (678 - 698)

7tmC_mGluR2

7tmC_mGluR2: cd15447 (723 - 749)

7tmC_mGluR2

7tmC_mGluR2: cd15447 (757 - 780)

7tmC_mGluR2

7tmC_mGluR2: cd15447 (787 - 812)

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  • 872 a.a.
蛋白主名 其他名称

metabotropic glutamate receptor 2

G protein-coupled receptor, family C, group 1, member B

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05822 GRM2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS05823 Grm2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS05824 Grm2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Grm2 NCBI NCBI:2912
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