1. Gene
  2. BTG3 - BTG anti-proliferation factor 3 Gene

BTG3 - BTG anti-proliferation factor 3 Gene

中文名称:BTG 抗增殖因子 3

种属: Homo sapiens

同用名: ANA; TOB5; TOFA; APRO4; TOB55; ANA/BTG3

基因 ID: 10950 | 基因类型: protein coding

关于 BTG3

Cytogenetic location: 21q21.1 Genomic coordinates (GRCh38): 21:17,593,653-17,612,901 (from NCBI)

This gene has 6 transcripts (splice variants), 1 gene allele, 181 orthologues and 3 paralogues. Ubiquitous expression in testis (RPKM 24.4), placenta (RPKM 23.0) and 25 other tissues.

功能概要

该基因编码的蛋白质是 BTG/Tob 家族的成员。该家族具有结构相关的蛋白质,这些蛋白质似乎具有抗增殖特性。这种编码的蛋白质可能在中枢神经系统的神经发生中发挥作用。已发现该基因的两个转录本变体编码不同的亚型。[RefSeq 提供,2008 年 8 月]

The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein might play a role in neurogenesis in the central nervous system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

BTG3 基因产物(2)

mRNA Protein Name
NM_001130914.2 NP_001124386.1 protein BTG3 isoform a
NM_006806.5 NP_006797.3 protein BTG3 isoform b

BTG3 蛋白结构

BTG

BTG: BTG family (1 - 117)

  • 0
  • 100
  • 200
  • 252 a.a.
蛋白主名 其他名称

protein BTG3

B-cell translocation gene 3

关联疾病

疾病名称 别名
Cataract 37

CTRCT37

Cca5

Cataract, Congenital, Cerulean Type, 5

Cataract 37, Autosomal Dominant

Congenital Cataract Cerulean Type 5

Enterokinase Deficiency

Enteropeptidase Deficiency

Congenital Enterokinase Deficiency

Congenital Enteropathy Due To Enteropeptidase Deficiency

Deficiency Of Enteropeptidase

ENTKD

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta BTG3 VGNC VGNC:70289
Mus musculus BTG3 MGD MGI:109532
Rattus norvegicus BTG3 RGD RGD:2226
Bos taurus BTG3 VGNC VGNC:26599
Felis catus BTG3 VGNC VGNC:60205
Canis familiaris BTG3 VGNC VGNC:38559