1. Gene
  2. DDX42 - DEAD-box helicase 42 Gene

DDX42 - DEAD-box helicase 42 Gene

中文名称:死盒解旋酶 42

种属: Homo sapiens

同用名: RHELP; RNAHP; SF3B8; DDX42P; SF3b125

基因 ID: 11325 | 基因类型: protein coding

关于 DDX42

Cytogenetic location: 17q23.3 Genomic coordinates (GRCh38): 17:63,773,800-63,819,317 (from NCBI)

This gene has 18 transcripts (splice variants), 211 orthologues and 38 paralogues. Ubiquitous expression in testis (RPKM 27.4), ovary (RPKM 25.5) and 25 other tissues.


该基因编码 Asp-Glu-Ala-Asp (DEAD) 盒蛋白家族的成员。该蛋白质家族的成员是推定的 RNA 解旋酶,并且涉及许多涉及 RNA 二级结构改变的细胞过程,例如翻译起始、核和线粒体剪接以及核糖体和剪接体组装。该家族的成员被认为参与胚胎发生、精子发生以及细胞生长和分裂。已为该基因鉴定出编码相同蛋白质的两个转录物变体。[RefSeq 提供,2008 年 7 月]

This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]

DDX42 基因产物(2)

mRNA Protein Name
NM_007372.3 NP_031398.2 ATP-dependent RNA helicase DDX42
NM_203499.3 NP_987095.1 ATP-dependent RNA helicase DDX42

DDX42 蛋白结构


DEAD: DEAD/DEAH box helicase (277 - 448)


Helicase_C: Helicase conserved C-terminal domain (517 - 593)

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  • 938 a.a.
蛋白主名 其他名称

ATP-dependent RNA helicase DDX42

DEAD (Asp-Glu-Ala-Asp) box helicase 42


种属 基因名 来源 基因 ID
Canis familiaris DDX42 VGNC VGNC:39858
Felis catus DDX42 VGNC VGNC:61409
Bos taurus DDX42 VGNC VGNC:27968
Macaca mulatta DDX42 VGNC VGNC:71661
Mus musculus DDX42 MGD MGI:1919297
Rattus norvegicus DDX42 RGD RGD:1304909