1. Gene
  2. EXOC3 - exocyst complex component 3 Gene

EXOC3 - exocyst complex component 3 Gene

中文名称:exocyst 复杂组件 3

种属: Homo sapiens

同用名: SEC6; Sec6p; SEC6L1

基因 ID: 11336 | 基因类型: protein coding

关于 EXOC3

Cytogenetic location: 5p15.33 Genomic coordinates (GRCh38): 5:443,176-467,290 (from NCBI)

This gene has 10 transcripts (splice variants), 212 orthologues and 4 paralogues. Ubiquitous expression in colon (RPKM 23.5), kidney (RPKM 21.1) and 25 other tissues.


由该基因编码的蛋白质是胞吐复合物的一个组成部分,胞吐复合物是一种多蛋白复合物,对于将胞吐囊泡靶向质膜上的特定停靠位点至关重要。尽管在酵母中得到了最好的表征,但已证明 exocyst 复合体的成分蛋白质和功能在高等真核生物中高度保守。发现 exocyst 复合物的至少八种成分 (包括这种蛋白质) 与肌动蛋白细胞骨架重塑和囊泡转运机制相互作用。该复合物对于上皮细胞表面极性的生物发生也是必不可少的。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008]

EXOC3 基因产物(1)

mRNA Protein Name
NM_007277.5 NP_009208.2 exocyst complex component 3

EXOC3 蛋白结构


Sec6: Exocyst complex component Sec6 (177 - 732)

  • 0
  • 200
  • 400
  • 600
  • 745 a.a.
蛋白主名 其他名称

exocyst complex component 3

SEC6-like 1


种属 基因名 来源 基因 ID
Macaca mulatta EXOC3 VGNC VGNC:72409
Canis familiaris EXOC3 VGNC VGNC:103674
Mus musculus EXOC3 MGD MGI:2443972
Bos taurus EXOC3 VGNC VGNC:28645
Felis catus EXOC3 VGNC VGNC:61999
Rattus norvegicus EXOC3 RGD RGD:621790