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  2. PIK3IP1 - phosphoinositide-3-kinase interacting protein 1 Gene

PIK3IP1 - phosphoinositide-3-kinase interacting protein 1 Gene

中文名称:磷酸肌醇 3 激酶相互作用蛋白 1

种属: Homo sapiens

同用名: HGFL; TrIP; hHGFL(S)

基因 ID: 113791 | 基因类型: protein coding

关于 PIK3IP1

Cytogenetic location: 22q12.2 Genomic coordinates (GRCh38): 22:31,281,593-31,292,534 (from NCBI)

This gene has 6 transcripts (splice variants), 218 orthologues and 5 paralogues. Ubiquitous expression in lymph node (RPKM 60.4), appendix (RPKM 38.3) and 23 other tissues.

功能概要

启用磷脂酰肌醇 3-激酶催化亚基结合活性。参与磷脂酰肌醇 3-激酶活性的负调节和磷脂酰肌醇 3-激酶信号的负调节。预测位于质膜中。预计是膜的组成部分。 [由基因组资源联盟提供,2022 年 4 月]

Enables phosphatidylinositol 3-kinase catalytic subunit binding activity. Involved in negative regulation of phosphatidylinositol 3-kinase activity and negative regulation of phosphatidylinositol 3-kinase signaling. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

PIK3IP1 基因产物(2)

mRNA Protein Name
NM_001135911.1 NP_001129383.1 phosphoinositide-3-kinase-interacting protein 1 isoform 2 precursor
NM_052880.5 NP_443112.2 phosphoinositide-3-kinase-interacting protein 1 isoform 1 precursor

PIK3IP1 蛋白结构

Kringle

Kringle: Kringle domain (25 - 87)

  • 0
  • 100
  • 200
  • 263 a.a.
蛋白主名 其他名称

phosphoinositide-3-kinase-interacting protein 1

PI3K-interacting protein 1

重组 PIK3IP1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71204 PIK3IP1 Protein, Human (HEK293, His) Q96FE7 (S22-T168) ≥95%

关联疾病

疾病名称 别名
Ovarian Clear Cell Carcinoma

Clear-Cell Ovarian Carcinoma

Endometrioid Ovary Carcinoma

Endometrioid Carcinoma Of Ovary

Endometrioid Carcinoma Ovary

Ovarian Endometrioid Carcinoma

Malignant Ovarian Endometrioid Tumor

Ovarian Endometrioid Tumor

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus PIK3IP1 VGNC VGNC:64177
Canis familiaris PIK3IP1 VGNC VGNC:44559
Bos taurus PIK3IP1 VGNC VGNC:32893
Rattus norvegicus PIK3IP1 RGD RGD:1311203
Mus musculus PIK3IP1 MGD MGI:1917016
Macaca mulatta PIK3IP1 VGNC VGNC:75859
Others PIK3IP1 NCBI